Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3345659 | 0.91 | HSD17B10 (0.55) | HSD17B10MAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL10005165 | 0.86 | MAPT (0.53) | HSD17B10MAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL10005128 | 0.86 | HSD17B10 (0.47) | HSD17B10MAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL10005074 | 0.82 | LMNA (0.53) | HSD17B10MAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL9042363 | 0.81 | RAB9A (0.63) | HSD17B10MAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL9045395 | 0.79 | HSD17B10 (0.56) | HSD17B10MAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL3337498 | 0.79 | HSD17B10 (0.53) | HSD17B10MAPTKDM4ESMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL10923922 | 0.74 | KMT2A (0.56) | MAPTKDM4ENPC1RAB9AMEN1 | |
| SCHEMBL27836376 | 0.73 | TOP2A (0.46) | HSD17B10MAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL10291489 | 0.73 | ALDH1A1 (0.51) | HSD17B10MAPTKDM4ESMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155892-B1 | NOVEL PEPTIDASE SUBSTRATES | BIOMERIEUX SA (FR) | 2015-03-18 | — | — | EP | disclosed |
| EP-2471944-A1 | Novel peptidase substrates | bioMérieux (FR) | 2012-07-04 | — | — | EP | disclosed |