Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 5/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3337498 | 0.83 | HSD17B10 (0.53) | MAPTPOLBHSD17B10NPSR1TP53 | |
| SCHEMBL10005074 | 0.83 | LMNA (0.53) | MAPTPOLBHSD17B10NPSR1TP53 | |
| SCHEMBL10005077 | 0.82 | MAPT (0.53) | MAPTPOLBTP53THRBNPC1 | |
| SCHEMBL10315955 | 0.79 | NPC1 (0.59) | MAPTPOLBHSD17B10NPSR1TDP1 | |
| SCHEMBL10291387 | 0.74 | NPC1 (0.62) | MAPTHSD17B10NPSR1TDP1TP53 | |
| SCHEMBL10005080 | 0.73 | CASP3 (0.55) | MAPTPOLBNPSR1TDP1TP53 | |
| SCHEMBL8964777 | 0.71 | KDM6B (0.61) | MAPTPOLBHSD17B10NPSR1TDP1 | |
| SCHEMBL29874275 | 0.70 | TP53 (0.76) | MAPTPOLBHSD17B10NPSR1TP53 | |
| SCHEMBL16156476 | 0.70 | TOP2A (0.62) | MAPTPOLBHSD17B10NPSR1TP53 | |
| SCHEMBL31048510 | 0.69 | C1R (0.64) | MAPTHSD17B10NPSR1TDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2471944-B1 | Novel peptidase substrates | BIOMERIEUX SA (FR) | 2016-09-14 | — | — | EP | disclosed |
| EP-2155892-B1 | NOVEL PEPTIDASE SUBSTRATES | BIOMERIEUX SA (FR) | 2015-03-18 | — | — | EP | disclosed |
| EP-2471944-A1 | Novel peptidase substrates | bioMérieux (FR) | 2012-07-04 | — | — | EP | disclosed |