SCHEMBL10007293

SCHEMBL10007293

C=C(C)C(=O)OCCOC(=O)/C=C/c1ccc(OC(=O)c2cc(N)cc(N)c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.46
KDM4E B2RXH2 3/20 0.46
LMNA P02545 4/20 0.41
TDP1 Q9NUW8 1/20 0.41
MET P08581 4/20 0.41
KMT2A Q03164 3/20 0.41
HSP90AA1 P07900 1/20 0.41
MAPK1 P28482 1/20 0.40
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA4 P22748 2/20 0.39
CA6 P23280 2/20 0.39
CA5A P35218 2/20 0.39
CA7 P43166 2/20 0.39
CA9 Q16790 2/20 0.39
CA14 Q9ULX7 2/20 0.39
CA5B Q9Y2D0 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
APP P05067 2/20 0.39
AKR1B10 O60218 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22354424 1.00 MAPT (0.46) MAPTKDM4ELMNATDP1MET
SCHEMBL15083727 0.97 MAPT (0.43) MAPTKDM4ELMNATDP1MET
SCHEMBL10296076 0.95 TDP1 (0.45) MAPTKDM4ELMNATDP1CA12
SCHEMBL15083761 0.90 TDP1 (0.43) KDM4ELMNATDP1METKMT2A
SCHEMBL13083869 0.89 MAPT (0.54) MAPTKDM4ELMNATDP1MET
SCHEMBL10296075 0.87 LMNA (0.44) LMNATDP1METCA12CA1
SCHEMBL10296154 0.87 MAPT (0.44) MAPTKDM4ELMNATDP1MET
SCHEMBL8158920 0.85 LMNA (0.54) MAPTKDM4ELMNATDP1KMT2A
SCHEMBL16024198 0.84 POLB (0.50) LMNATDP1CA12CA1CA4
SCHEMBL15083776 0.84 ALOX5 (0.47) MAPTKDM4ELMNATDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013099804-A1 LIQUID CRYSTAL ORIENTATION AGENT, LIQUID CRYSTAL ORIENTATION MEMBRANE, LIQUID CRYSTAL DISPLAY ELEMENT, AND DIAMINE COMPOUND 日産化学工業株式会社 (JP) 2013-07-04 WO disclosed
US-20120172541-A1 Liquid Crystal Alignment Agent, Liquid Crystal Alignment Film Manufactured Using the Same, and Liquid Crystal Display Device Including the Liquid Crystal Alignment Film CHEIL INDUSTRIES INC. (KR) 2012-07-05 US disclosed
US-20120172541-A1 Liquid Crystal Alignment Agent, Liquid Crystal Alignment Film Manufactured Using the Same, and Liquid Crystal Display Device Including the Liquid Crystal Alignment Film CHEIL INDUSTRIES INC. (KR) 2012-07-05 US disclosed
US-20120172541-A1 Liquid Crystal Alignment Agent, Liquid Crystal Alignment Film Manufactured Using the Same, and Liquid Crystal Display Device Including the Liquid Crystal Alignment Film CHEIL INDUSTRIES INC. (KR) 2012-07-05 US disclosed