SCHEMBL10010079

SCHEMBL10010079

C=Cc1ccc(OCC2CCC(Cc3c(C(=O)O)ccc(C(=O)O)c3CC3CCC(COc4ccc(C=C)cc4)CC3)CC2)cc1

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 7/20 0.45
PARP15 Q460N3 6/20 0.45
PARP2 Q9UGN5 2/20 0.45
NR1H4 Q96RI1 1/20 0.40
HPGD P15428 5/20 0.39
GPR88 Q9GZN0 1/20 0.38
PPARG P37231 1/20 0.37
PPARD Q03181 1/20 0.37
PPARA Q07869 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15514489 0.81 PARP15 (0.50) PARP10PARP15PARP2HPGD
SCHEMBL216951 0.79 PARP15 (0.32) PARP10PARP15PARP2
SCHEMBL9943601 0.75 PARP15 (0.55) PARP10PARP15PARP2NR1H4HPGD
SCHEMBL416244 0.70 PARP15 (0.72) PARP10PARP15PARP2NR1H4
SCHEMBL1073031 0.70 ESR1 (0.38)
SCHEMBL28388153 0.69 NPC1 (0.47) PARP10PARP15PARP2NR1H4
SCHEMBL1389367 0.69
SCHEMBL15969380 0.69 PARP10 (0.50) PARP10PARP15PARP2NR1H4PPARA
SCHEMBL927683 0.69 PARP10 (0.68) PARP10PARP15PARP2NR1H4PPARD
SCHEMBL1390989 0.69 PARP10 (0.53) PARP10PARP15PARP2NR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9598553-B2 Metal nanoparticle composite and method for producing the same MARUZEN PETROCHEMICAL CO., LTD. (JP) 2017-03-21 US disclosed
US-20140058028-A1 METAL NANOPARTICLE COMPOSITE AND METHOD FOR PRODUCING THE SAME MARUZEN PETROCHEMICAL CO., LTD. (JP) 2014-02-27 US disclosed
US-20120172535-A1 VINYL ETHER-BASED STAR POLYMER AND PROCESS FOR PRODUCTION THEREOF MARUZEN PETROCHEMICAL CO., LTD. (JP) 2012-07-05 US disclosed