Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 4/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.50 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9943601 | 0.84 | PARP15 (0.55) | PARP15PARP10PARP2HPGDCHRNB2 | |
| SCHEMBL29024848 | 0.83 | PARP15 (0.64) | PARP15PARP10PARP2TDP1SIGMAR1 | |
| SCHEMBL19834476 | 0.83 | ACACA (0.52) | — | |
| SCHEMBL572868 | 0.83 | CHRNB2 (0.39) | PARP15PARP10PARP2HPGDCHRNB2 | |
| SCHEMBL8314306 | 0.81 | PARP15 (0.54) | PARP15PARP10PARP2HPGDTDP1 | |
| SCHEMBL3718600 | 0.81 | PARP15 (0.54) | PARP15PARP10PARP2HPGDTDP1 | |
| SCHEMBL8312964 | 0.81 | PARP15 (0.54) | PARP15PARP10PARP2HPGDTDP1 | |
| SCHEMBL10010079 | 0.81 | PARP10 (0.45) | PARP15PARP10PARP2HPGD | |
| SCHEMBL573151 | 0.78 | TDP1 (0.59) | HPGDTDP1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL3828236 | 0.78 | TDP1 (0.59) | HPGDTDP1CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220396583-A1 | COMPOUNDS AS MODULATORS OF TLR2 SIGNALING | NEUROPORE THERAPIES, INC. (US) | 2022-12-15 | — | — | US | disclosed |
| US-11345713-B2 | Compounds as modulators of TLR2 signaling | NEUROPORE THERAPIES, INC. (US) | 2022-05-31 | — | — | US | disclosed |
| EP-3774736-A1 | COMPOUNDS AS MODULATORS OF TLR2 SIGNALING | Neuropore Therapies, Inc. (US) | 2021-02-17 | — | — | EP | disclosed |
| US-20210024539-A1 | COMPOUNDS AS MODULATORS OF TLR2 SIGNALING | NEUROPORE THERAPIES, INC. (US) | 2021-01-28 | — | — | US | disclosed |
| WO-2019191189-A1 | COMPOUNDS AS MODULATORS OF TLR2 SIGNALING | NEUROPORE THERAPIES, INC. (US) | 2019-10-03 | — | — | WO | disclosed |
| WO-2019191189-A1 | COMPOUNDS AS MODULATORS OF TLR2 SIGNALING | NEUROPORE THERAPIES, INC. (US) | 2019-10-03 | — | — | WO | disclosed |
| EP-2797110-B1 | INSULATION-LAYER MATERIAL FOR ELECTRONIC DEVICE, AND ELECTRONIC DEVICE | SUMITOMO CHEMICAL CO (JP) | 2018-02-28 | — | — | EP | disclosed |
| US-9461257-B2 | Electronic device insulating layer, and method for producing electronic device insulating layer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-10-04 | — | — | US | disclosed |
| CN-104040700-B | Insulating electronic device layer material and electronic device | 住友化学株式会社 | 2016-09-07 | — | — | CN | disclosed |
| US-9362512-B2 | Electronic device insulating layer material capable of forming an insulating layer at low temperature | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-06-07 | — | — | US | disclosed |
| US-20150236281-A1 | INSULATION-LAYER MATERIAL FOR ELECTRONIC DEVICE, AND ELECTRONIC DEVICE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-08-20 | — | — | US | disclosed |
| US-9035292-B2 | Organic thin-film transistor insulating layer material | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-05-19 | — | — | US | disclosed |
| US-20150008418-A1 | ELECTRONIC DEVICE INSULATING LAYER, AND METHOD FOR PRODUCING ELECTRONIC DEVICE INSULATING LAYER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-01-08 | — | — | US | disclosed |
| CN-104137236-A | Electronic device insulating layer and method for manufacturing electronic device insulating layer | SUMITOMO CHEMICAL CO | 2014-11-05 | — | — | CN | disclosed |
| EP-2797110-A1 | INSULATION-LAYER MATERIAL FOR ELECTRONIC DEVICE, AND ELECTRONIC DEVICE | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2014-10-29 | — | — | EP | disclosed |
| CN-104040700-A | INSULATION-LAYER MATERIAL FOR ELECTRONIC DEVICE, AND ELECTRONIC DEVICE | SUMITOMO CHEMICAL CO | 2014-09-10 | — | — | CN | disclosed |
| US-20140070205-A1 | ORGANIC THIN-FILM TRANSISTOR INSULATING LAYER MATERIAL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11345713-B2 | Compounds as modulators of TLR2 signaling | TLR2, TLR4, TLR3 | PARP15 1928/4885PARP10 1695/4885PARP2 1801/4885 |
| US-20220396583-A1 | COMPOUNDS AS MODULATORS OF TLR2 SIGNALING | TLR2, TLR4, TLR3 | PARP15 1928/4885PARP10 1695/4885PARP2 1801/4885 |
| US-20210024539-A1 | COMPOUNDS AS MODULATORS OF TLR2 SIGNALING | TLR2, TLR4, TLR3 | PARP15 1928/4885PARP10 1695/4885PARP2 1801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.