SCHEMBL1001010

SCHEMBL1001010

CCCCCCCCCc1ccccc1OP(O)(=S)S

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.53
THRB P10828 1/20 0.53
LIPG Q9Y5X9 1/20 0.47
ALOX5 P09917 1/20 0.47
PTGS2 P35354 1/20 0.47
PPARA Q07869 3/20 0.46
PPARG P37231 2/20 0.46
BID P55957 3/20 0.41
MCL1 Q07820 3/20 0.41
BCL2L1 Q07817 2/20 0.41
BAK1 Q16611 2/20 0.41
KAT8 Q9H7Z6 2/20 0.41
EP300 Q09472 1/20 0.41
KAT2A Q92830 1/20 0.41
KAT2B Q92831 1/20 0.41
KAT5 Q92993 1/20 0.41
SAE1 Q9UBE0 1/20 0.41
ENPP2 Q13822 1/20 0.39
LTB4R Q15722 1/20 0.38
LTB4R2 Q9NPC1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3929117 1.00 THRA (0.53) THRATHRBLIPGALOX5PTGS2
SCHEMBL4980580 1.00 THRA (0.53) THRATHRBLIPGALOX5PTGS2
SCHEMBL27275672 0.99 THRA (0.52) THRATHRBLIPGALOX5PTGS2
Water SCHEMBL27918100 0.99 THRA (0.52) THRATHRBLIPGALOX5PTGS2
SCHEMBL10625276 0.99 THRA (0.52) THRATHRBLIPGALOX5PTGS2
Hydrogen Sulfide SCHEMBL4610063 0.99 THRA (0.52) THRATHRBLIPGALOX5PTGS2
Water SCHEMBL27424481 0.97 THRA (0.51) THRATHRBLIPGALOX5PTGS2
Hydrogen Sulfide SCHEMBL9821128 0.97 THRA (0.51) THRATHRBLIPGALOX5PTGS2
SCHEMBL27734403 0.96 THRA (0.53) THRATHRBLIPGALOX5PTGS2
SCHEMBL999141 0.94 THRA (0.46) THRATHRBLIPGALOX5PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0208541-B1 LUBRICANT COMPOSITIONS NIPPON OIL CO. LTD. (JP) 1991-12-04 EP claimed
CN-117402663-A Molybdenum-containing transmission lubricant 雅富顿化学公司 2024-01-16 CN disclosed
CN-101978036-B Lubricant composition for internal combustion engine JX NIPPON OIL & ENERGY CORP. (JP) 2016-04-13 CN disclosed
CN-102177227-B Lubricant composition and method for producing same JX NIPPON OIL & ENERGY CORP 2013-12-18 CN disclosed
CN-101432408-B Grease composition for constant velocity joints SHOWA SHELL SEKIYU 2012-04-04 CN disclosed
CN-102177227-A Lubricant composition and method for producing same JX NIPPON OIL & ENERGY CORP 2011-09-07 CN disclosed
CN-101978036-A Lubricant oil composition for internal combustion engine JX NIPPON OIL & ENERGY CORP 2011-02-16 CN disclosed
US-7867957-B2 Lubricating oil composition NIPPON OIL CORPORATION (JP) 2011-01-11 US disclosed
CN-101432408-A Grease composition for constant velocity joints SHOWA SHELL SEKIYU (JP) 2009-05-13 CN disclosed
EP-2054491-A1 GREASE COMPOSITION FOR CONSTANT VELOCITY JOINTS Showa Shell Sekiyu Kabushiki Kaisha (JP) 2009-05-06 EP disclosed
CN-101395257-A Grease composition SHELL INT RESEARCH (NL) 2009-03-25 CN disclosed
EP-1979449-A1 GREASE COMPOSITION Shell Internationale Research Maatschappij B.V. (NL) 2008-10-15 EP disclosed
US-20080248981-A1 Lubricating base oil, an ashless friction modifier and a phosphorus-containing anti-wear agent; increasing the isomerization rate from normal paraffins to isoparaffins, improving the low temperature viscosity property by lowering the viscosity of the lubricating base oil NIPPON OIL CORPORATION 2008-10-09 US disclosed
US-20080234153-A1 LUBRICATING OIL COMPOSITION NIPPON OIL CORPORATION (JP) 2008-09-25 US disclosed
WO-2007129775-A1 GREASE COMPOSITION FOR CONSTANT VELOCITY JOINTS SHOWA SHELL SEKIYU K.K. (JP) 2007-11-15 WO disclosed
WO-2007085643-A1 GREASE COMPOSITION SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2007-08-02 WO disclosed