SCHEMBL10010189

SCHEMBL10010189

O=S(=O)(O)c1ccc(O)cc1I

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.44
HPGD P15428 1/20 0.44
HIF1A Q16665 1/20 0.44
HSD17B10 Q99714 1/20 0.44
PTGS1 P23219 1/20 0.39
EGFR P00533 1/20 0.39
MPL P40238 2/20 0.39
NSD2 O96028 2/20 0.38
MMP14 P50281 2/20 0.38
CASP6 P55212 2/20 0.38
ESR1 P03372 1/20 0.37
MAOA P21397 1/20 0.37
UGT1A1 P22309 1/20 0.37
MAOB P27338 1/20 0.37
ESR2 Q92731 1/20 0.37
TET2 Q6N021 1/20 0.37
POLB P06746 2/20 0.36
GAA P10253 1/20 0.36
GFER P55789 1/20 0.36
ALPL P05186 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18066938 0.84 LMNA (0.50) LMNAHPGDHIF1AHSD17B10PTGS1
SCHEMBL25314802 0.81 ENPP2 (0.45) LMNAHPGDHIF1AHSD17B10PTGS1
SCHEMBL30507246 0.81 ENPP2 (0.45) LMNAHPGDHIF1AHSD17B10PTGS1
SCHEMBL2848985 0.80 TET2 (0.41) LMNAHPGDHIF1AHSD17B10TET2
SCHEMBL5664509 0.79 LMNA (0.53) LMNAHPGDHIF1AHSD17B10PTGS1
SCHEMBL17272337 0.77 LMNA (0.52) LMNAHPGDHIF1AHSD17B10PTGS1
SCHEMBL17272356 0.77 LMNA (0.52) LMNAHPGDHIF1AHSD17B10PTGS1
SCHEMBL7543699 0.77 LMNA (0.52) LMNAHPGDHIF1AHSD17B10PTGS1
Ammonia Solution, Strong SCHEMBL17272232 0.77 LMNA (0.52) LMNAHPGDHIF1AHSD17B10PTGS1
SCHEMBL669162 0.77 LMNA (0.52) LMNAHPGDHIF1AHSD17B10PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9283402-B2 Apparatus and method for providing a double balloon breast brachytherapy device BEST MEDICAL INTERNATIONAL, INC. (US) 2016-03-15 US disclosed
US-20120172651-A1 Apparatus and Method for providing a Double Balloon Breast Brachytherapy Device Best Medical International, Inc (US) 2012-07-05 US disclosed
CN-1901970-A Brachytherapy device and method for treating target tissue through external surface CYTYC CORP (US) 2007-01-24 CN disclosed