Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | F7 | P08709 | 3/20 | 0.45 |
| ▸ | F3 | P13726 | 3/20 | 0.45 |
| ▸ | FABP3 | P05413 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | GNA15 | P30679 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10010430 | 1.00 | ALDH1A1 (0.45) | ALDH1A1KDM4EF7F3FABP3 | |
| SCHEMBL10009115 | 1.00 | ALDH1A1 (0.45) | ALDH1A1KDM4EF7F3FABP3 | |
| SCHEMBL10009117 | 1.00 | ALDH1A1 (0.45) | ALDH1A1KDM4EF7F3FABP3 | |
| SCHEMBL15220042 | 0.87 | FFAR1 (0.42) | F7F3FABP3PPARGPPARD | |
| SCHEMBL16534482 | 0.87 | FFAR1 (0.42) | F7F3FABP3PPARGPPARD | |
| SCHEMBL3892975 | 0.86 | ALDH1A1 (0.50) | ALDH1A1HPGDTDP1 | |
| SCHEMBL19019739 | 0.85 | ALDH1A1 (0.43) | ALDH1A1KDM4EF7F3FABP3 | |
| SCHEMBL21192736 | 0.85 | GPR84 (0.42) | KDM4EFFAR1LMNACYP3A4 | |
| SCHEMBL28903645 | 0.85 | GPR84 (0.42) | KDM4EFFAR1LMNACYP3A4 | |
| SCHEMBL1735175 | 0.82 | MAPT (0.46) | ALDH1A1KDM4ELMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140288146-A1 | NOVEL TRIALKYL CATIONIC LIPIDS AND METHODS OF USE THEREOF | PROTIVA BIOTHERAPEUTICS, INC. (CA) | 2014-09-25 | — | — | US | disclosed |
| US-8466122-B2 | Trialkyl cationic lipids and methods of use thereof | PROTIVA BIOTHERAPEUTICS, INC. (CA) | 2013-06-18 | — | — | US | disclosed |
| US-20120172411-A1 | NOVEL TRIALKYL CATIONIC LIPIDS AND METHODS OF USE THEREOF | PROTIVA BIOTHERAPEUTICS, INC. (CA) | 2012-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140288146-A1 | NOVEL TRIALKYL CATIONIC LIPIDS AND METHODS OF USE THEREOF | NPC1L1, LDLR, CETP | ALDH1A1 4746/4885KDM4E 4459/4885F7 3898/4885 |
| US-20120172411-A1 | NOVEL TRIALKYL CATIONIC LIPIDS AND METHODS OF USE THEREOF | NPC1L1, LDLR, CETP | ALDH1A1 4746/4885KDM4E 4459/4885F7 3898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.