Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1001088 | 1.00 | TLR4 (0.36) | TLR4 | |
| SCHEMBL12926630 | 1.00 | TLR4 (0.36) | TLR4 | |
| SCHEMBL1001089 | 1.00 | TLR4 (0.36) | TLR4 | |
| SCHEMBL12926633 | 0.90 | CYP1A2 (0.39) | — | |
| SCHEMBL12926635 | 0.90 | TLR4 (0.35) | TLR4 | |
| SCHEMBL12926747 | 0.84 | TLR4 (0.35) | TLR4 | |
| SCHEMBL12926641 | 0.83 | TLR4 (0.33) | TLR4 | |
| SCHEMBL12926615 | 0.82 | CYP1A2 (0.34) | TLR4 | |
| SCHEMBL12926593 | 0.82 | KMT2A (0.33) | TLR4 | |
| SCHEMBL12926594 | 0.82 | TLR4 (0.40) | TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7875327-B2 | nematic phase consisting of a lactone ring of pyranone, a cyclohexylene or 1,4-phenylene ring, or replaced by one or more fluorine; controlling temperature, optical and dielectric anisotropy, photostability, heat resistance | CHISSO CORPORATION (JP) | 2011-01-25 | — | — | US | disclosed |
| US-20100038588-A1 | Liquid Crystal Compound Having Lactone Ring, Liquid Crystal Composition, And Liquid Crystal Display Device | CHISSO CORPORATION (JP) | 2010-02-18 | — | — | US | disclosed |
| US-7618688-B2 | Liquid crystal compound having lactone ring, liquid crystal composition, and liquid crystal display device | CHISSO CORPORATION (JP) | 2009-11-17 | — | — | US | disclosed |
| EP-1785467-B1 | Liquid crystal compound having lactone ring, liquid crystal composition, and liquid crystal display device | CHISSO CORP (JP) | 2009-03-18 | — | — | EP | disclosed |
| US-20070108410-A1 | Liquid crystal compound having lactone ring, liquid crystal composition, and liquid crystal display device | CHISSO CORPORATION | 2007-05-17 | — | — | US | disclosed |
| EP-1785467-A1 | Liquid crystal compound having lactone ring, liquid crystal composition, and liquid crystal display device | CHISSO CORPORATION (JP) | 2007-05-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100038588-A1 | Liquid Crystal Compound Having Lactone Ring, Liquid Crystal Composition, And Liquid Crystal Display Device | TCF7L2, TCF7, CA7 | TLR4 3225/4885 |
| US-20070108410-A1 | Liquid crystal compound having lactone ring, liquid crystal composition, and liquid crystal display device | TCF7L2, TCF7, CA7 | TLR4 3219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.