Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CXCR2 | P25025 | 7/20 | 0.54 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | BRAF | P15056 | 2/20 | 0.46 |
| ▸ | DDX3X | O00571 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29773126 | 0.83 | TSHR (0.55) | CYP3A4TSHRCXCR2ALOX5BRAF | |
| SCHEMBL8834026 | 0.82 | BRAF (0.72) | CYP3A4CXCR2CXCR1BRAFCHEK1 | |
| SCHEMBL4707292 | 0.80 | CXCR2 (0.73) | CXCR2CXCR1GAAMEN1KMT2A | |
| SCHEMBL7003152 | 0.80 | GAA (0.60) | CYP3A4TSHRCXCR2BRAFGAA | |
| SCHEMBL28032578 | 0.80 | GAA (0.62) | CYP3A4TSHRBRAFGAAALDH1A1 | |
| SCHEMBL31047645 | 0.80 | CXCR2 (0.73) | CXCR2CXCR1GAAMEN1KMT2A | |
| SCHEMBL7003540 | 0.80 | ALDH1A1 (0.65) | CYP3A4TSHRCXCR2BRAFGAA | |
| SCHEMBL7169368 | 0.80 | CYP3A4 (0.52) | CYP3A4TSHRBRAFGAAALDH1A1 | |
| SCHEMBL9443917 | 0.80 | ALDH1A1 (0.65) | CYP3A4TSHRCXCR2CXCR1GAA | |
| SCHEMBL29720861 | 0.78 | CXCR2 (0.68) | CYP3A4TSHRCXCR2GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4494953-A | 2,4-Dihydroxydiphenylamines and hair dyeing compositions and method | L'OREAL (FR) | 1985-01-22 | — | — | US | claimed |
| US-4263213-A | 2,4-Dihydroxy-4'-(substituted amino)-diphenylamines | L'OREAL (FR) | 1981-04-21 | — | — | US | claimed |
| EP-2479203-A1 | AROMATIC POLYESTER | Muroran Institute of Technology (JP) | 2012-07-25 | — | — | EP | disclosed |
| US-20120172570-A1 | AROMATIC POLYESTER | NITTA CORPORATION | 2012-07-05 | — | — | US | disclosed |
| US-4737438-A | Negative-working photosensitive composition comprising a diphenylamine-melamine condensate and an azide compound | TOKYO OHKA KOGYO CO., LTD. (JP) | 1988-04-12 | — | — | US | disclosed |
| US-4494953-A | 2,4-Dihydroxydiphenylamines and hair dyeing compositions and method | L'OREAL (FR) | 1985-01-22 | — | — | US | disclosed |
| US-4494953-A | 2,4-Dihydroxydiphenylamines and hair dyeing compositions and method | L'OREAL (FR) | 1985-01-22 | — | — | US | disclosed |
| US-4263213-A | 2,4-Dihydroxy-4'-(substituted amino)-diphenylamines | L'OREAL (FR) | 1981-04-21 | — | — | US | disclosed |