Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | CASP1 | P29466 | 1/20 | 0.60 |
| ▸ | CASP7 | P55210 | 1/20 | 0.60 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.60 |
| ▸ | CBFB | Q13951 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | TNIK | Q9UKE5 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.47 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7003046 | 0.85 | GAA (0.53) | GAAMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL7001007 | 0.84 | RAPGEF4 (0.53) | GAAMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL7644039 | 0.83 | GAA (0.61) | GAAMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL11341031 | 0.82 | GAA (0.62) | GAAMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL28260920 | 0.81 | GAA (0.53) | GAAMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL22887353 | 0.81 | CDC25B (0.58) | — | |
| Benzene SCHEMBL29197172 | 0.80 | GAA (0.62) | GAAMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL429859 | 0.80 | GAA (0.62) | GAAMAPTLMNACXCR2RAPGEF4 | |
| SCHEMBL8738783 | 0.80 | GAA (0.62) | GAAMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL29473561 | 0.80 | GAA (0.62) | GAAMAPTLMNACXCR2RAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10377713-B2 | Quencher | FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) | 2019-08-13 | — | — | US | disclosed |
| US-20170342031-A1 | QUENCHER | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2017-11-30 | — | — | US | disclosed |
| US-20170342031-A1 | QUENCHER | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2017-11-30 | — | — | US | disclosed |
| EP-3235876-A1 | QUENCHER | Wako Pure Chemical Industries, Ltd. (JP) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016098889-A1 | QUENCHER | 和光純薬工業株式会社 | 2016-06-23 | — | — | WO | disclosed |
| US-6635602-B1 | Heat sensitive and pressure sensitive recording material; synthesised directly by the reaction of two derivatives of amino phenols, phthalic anhydrides, keto acids and/or diphenylamines with a phenol derivative | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-10-21 | — | — | US | disclosed |
| US-6566302-B1 | For use in heat sensitive and pressure sensitive recording materials | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-05-20 | — | — | US | disclosed |
| EP-1107972-B1 | PREPARATION PROCESS FOR MANUFACTURE AND PURIFICATION OF MIXTURES OF FLUORAN COMPOUNDS AND RECORDING MATERIAL COMPRISING SAID MIXTURES OF FLUORAN | CIBA SC HOLDING AG (CH) | 2003-01-02 | — | — | EP | disclosed |
| EP-1115579-B1 | MONOPHASE SOLID SOLUTIONS COMPRISING A PLURALITY OF COLOUR FORMER COMPOUNDS AND PROCESS FOR THEIR PREPARATION | CIBA SC HOLDING AG (CH) | 2002-11-20 | — | — | EP | disclosed |
| EP-1115579-A1 | MONOPHASE SOLID SOLUTIONS COMPRISING A PLURALITY OF COLOUR FORMER COMPOUNDS AND PROCESS FOR THEIR PREPARATION | Ciba SC Holding AG (CH) | 2001-07-18 | — | — | EP | disclosed |
| US-4677203-A | Chromogenic fluoran derivatives | SHIN NISSO KAKO CO., LTD. (JP) | 1987-06-30 | — | — | US | disclosed |
| EP-0176161-A1 | Novel fluoran compounds and production and use thereof | TAOKA CHEMICAL CO., LTD (JP) | 1986-04-02 | — | — | EP | disclosed |
| US-4410708-A | Chromogenic fluoran derivatives and the preparation and use thereof | SHIN NISSO KAKO CO., LTD. (JP) | 1983-10-18 | — | — | US | disclosed |
| US-4341403-A | Fluoran compounds, process for preparation thereof, and recording sheets using same | FUJI PHOTO FILM CO., LTD. (JP) | 1982-07-27 | — | — | US | disclosed |
| US-4187193-A | Micro-capsules containing ureido fluoran chromogenic compounds | CHAMPION INTERNATIONAL CORPORATION (US) | 1980-02-05 | — | — | US | disclosed |
| US-4147880-A | Age resisters and age resistant polymeric compositions | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1979-04-03 | — | — | US | disclosed |
| US-4104437-A | Pressure-sensitive copy system including ureido fluoran chromogenic compounds | CHAMPION INTERNATIONAL CORPORATION (US) | 1978-08-01 | — | — | US | disclosed |
| US-4007195-A | LEUCO DYES | CIBA-GEIGY AG (CH) | 1977-02-08 | — | — | US | disclosed |
| US-3959571-A | PRESSURE OR HEAT SENSITIVE COPYING PAPER | SHIN NISSO KAKO CO., LTD. (JA) | 1976-05-25 | — | — | US | disclosed |
| US-3953411-A | Age resistant polymers of 4-(arylamino)aryl esters of α,β unsaturated carboxylic acids | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1976-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10377713-B2 | Quencher | AHR, GFER, AKR1A1 | GAA 4560/4885MAPT 4848/4885KDM4E 3254/4885 |
| US-20170342031-A1 | QUENCHER | AHR, GFER, AKR1A1 | GAA 4560/4885MAPT 4848/4885KDM4E 3254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.