SCHEMBL10011074

SCHEMBL10011074

[O]C(=O)c1ccc(C2CCCCC2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 2/20 0.61
HDAC6 Q9UBN7 2/20 0.61
HDAC1 Q13547 1/20 0.61
HAO1 Q9UJM8 1/20 0.57
DEGS1 O15121 2/20 0.54
HDAC3 O15379 1/20 0.54
HDAC11 Q96DB2 1/20 0.54
KMO O15229 1/20 0.49
NAMPT P43490 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.47
ACMSD Q8TDX5 2/20 0.47
HTT P42858 2/20 0.47
KDM4E B2RXH2 1/20 0.47
GLA P06280 1/20 0.47
KMT2A Q03164 1/20 0.47
HIF1A Q16665 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
SLC6A7 Q99884 1/20 0.47
ALDH1A1 P00352 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL7018415 0.86 KMO (0.61) HDAC8HDAC6HDAC1HAO1DEGS1
SCHEMBL341579 0.85 HDAC8 (0.63) HDAC8HDAC6HDAC1HAO1DEGS1
SCHEMBL22291720 0.83 KMO (0.62) HDAC8HDAC6HDAC1HAO1DEGS1
SCHEMBL354930 0.83 KMO (0.62) HDAC8HDAC6HDAC1HAO1DEGS1
SCHEMBL4742964 0.83 HDAC8 (0.66) HDAC8HDAC6HDAC1HAO1DEGS1
SCHEMBL1531069 0.82 HDAC8 (0.59) HDAC8HDAC6HDAC1HAO1DEGS1
SCHEMBL15081033 0.82 HDAC8 (0.59) HDAC8HDAC6HDAC1HAO1DEGS1
SCHEMBL2744667 0.82 HDAC8 (0.59) HDAC8HDAC6HDAC1HAO1DEGS1
SCHEMBL6822864 0.82 HDAC8 (0.59) HDAC8HDAC6HDAC1HAO1DEGS1
SCHEMBL12813895 0.82 HDAC8 (0.59) HDAC8HDAC6HDAC1HAO1DEGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2478981-B1 SILVER-(CONJUGATED COMPOUND) COMPLEX SUMITOMO CHEMICAL CO (JP) 2020-12-23 EP disclosed
US-9704612-B2 Composition of silver-conjugated compound composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-11 US disclosed
US-9412487-B2 Silver-(conjugated compound) composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-08-09 US disclosed
US-20140001422-A1 COMPOSITION OF SILVER-CONJUGATED COMPOUND COMPOSITE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-02 US disclosed
EP-2478981-A1 SILVER-(CONJUGATED COMPOUND) COMPLEX Sumitomo Chemical Co., Ltd (JP) 2012-07-25 EP disclosed
US-20120168693-A1 SILVER-(CONJUGATED COMPOUND) COMPOSITE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-05 US disclosed