Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.66 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.56 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.47 |
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL341579 | 0.98 | HDAC8 (0.63) | HDAC8HDAC6HDAC1HAO1DEGS1 | |
| SCHEMBL9860574 | 0.95 | HDAC8 (0.60) | HDAC8HDAC6HDAC1HAO1DEGS1 | |
| SCHEMBL7357954 | 0.91 | HDAC8 (0.53) | HDAC8HDAC6HDAC1HAO1DEGS1 | |
| SCHEMBL11218828 | 0.90 | KMO (0.57) | HDAC8HDAC6HDAC1HAO1DEGS1 | |
| SCHEMBL3495930 | 0.84 | HDAC8 (0.63) | HDAC8HDAC6HDAC1HAO1DEGS1 | |
| SCHEMBL11576463 | 0.84 | ALDH1A1 (0.67) | HDAC8HDAC6HDAC1HAO1SMN1; SMN2 | |
| SCHEMBL10943927 | 0.84 | HDAC8 (0.50) | HDAC8HDAC6HDAC1HAO1DEGS1 | |
| SCHEMBL8945320 | 0.83 | PGR (0.58) | HDAC8HDAC6HDAC1HAO1SRD5A2 | |
| SCHEMBL354930 | 0.83 | KMO (0.62) | HDAC8HDAC6HDAC1HAO1DEGS1 | |
| SCHEMBL10011074 | 0.83 | HDAC8 (0.61) | HDAC8HDAC6HDAC1HAO1DEGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201991-A | Methods and compositions for reducing solvent release from agrochemical formulations and reducing agrochemical formulation odor | 安道麦马克西姆有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-118201991-A | Methods and compositions for reducing solvent release from agrochemical formulations and reducing agrochemical formulation odor | 安道麦马克西姆有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-118027260-A | High-selectivity polymer material with adjustable repeating unit carbon skeleton structure and preparation method thereof | 大连理工大学 | 2024-05-14 | — | — | CN | disclosed |
| CN-116282078-A | Salt recovery solution and method of using the same | 阿克福特斯技术有限公司 | 2023-06-23 | — | — | CN | disclosed |
| WO-2023085225-A1 | METHOD FOR MANUFACTURING RECYCLED RESIN COMPOSITION | 住友化学株式会社 | 2023-05-19 | — | — | WO | disclosed |
| CN-113785023-B | Water-based ink composition for reversible thermochromic writing instrument, refill for refill and water-based ballpoint pen incorporating same | 株式会社百乐 | 2023-05-12 | — | — | CN | disclosed |
| CN-113891760-A | Solvent drying compositions and related methods | 阿克福特斯技术有限公司 | 2022-01-04 | — | — | CN | disclosed |
| CN-111225875-A | Salt recovery solution and method of using salt recovery solution | 阿克福特斯技术有限公司 | 2020-06-02 | — | — | CN | disclosed |
| WO-2008096093-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | disclosed |
| EP-0468974-A4 | NOVEL HMG-COA REDUCTASE INHIBITORS | — | 1992-03-25 | — | — | EP | disclosed |
| EP-0468974-A1 | NOVEL HMG-CoA REDUCTASE INHIBITORS | RORER INTERNATIONAL (HOLDINGS), INC. (US) | 1992-02-05 | — | — | EP | disclosed |
| US-5001128-A | HMG-COA reductase inhibitors | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1991-03-19 | — | — | US | disclosed |
| WO-1990010444-A1 | NOVEL HMG-CoA REDUCTASE INHIBITORS | RORER INTERNATIONAL (HOLDINGS), INC. (US) | 1990-09-20 | — | — | WO | disclosed |
| US-4904691-A | Novel HMG-CoA reductase inhibitors | RORER PHARMACEUTICAL CORPORATION (US) | 1990-02-27 | — | — | US | disclosed |
| US-4407823-A | ANTIINFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1983-10-04 | — | — | US | disclosed |
| US-4377689-A | Process for preparing spiro derivatives | ETABLISSEMENTS NATIVELLE S.A. (FR) | 1983-03-22 | — | — | US | disclosed |
| US-4371538-A | Spiro derivatives, process for their preparation and medications containing same | ETABLISSEMENTS NATIVELLE S.A. (FR) | 1983-02-01 | — | — | US | disclosed |