Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.33 |
| ▸ | TOP1 | P11387 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL616881 | 1.00 | LMNA (0.42) | LMNAL3MBTL1TDP1AKR1B1KDM4E | |
| SCHEMBL64935 | 1.00 | LMNA (0.42) | LMNAL3MBTL1TDP1AKR1B1KDM4E | |
| SCHEMBL368405 | 1.00 | LMNA (0.42) | LMNAL3MBTL1TDP1AKR1B1KDM4E | |
| SCHEMBL3130561 | 0.94 | LMNA (0.46) | LMNAL3MBTL1TDP1AKR1B1KDM4E | |
| SCHEMBL33584 | 0.94 | LMNA (0.46) | LMNAL3MBTL1TDP1AKR1B1KDM4E | |
| SCHEMBL1369560 | 0.94 | LMNA (0.46) | LMNAL3MBTL1TDP1AKR1B1KDM4E | |
| SCHEMBL4126076 | 0.94 | LMNA (0.46) | LMNAL3MBTL1TDP1AKR1B1KDM4E | |
| SCHEMBL3128140 | 0.94 | LMNA (0.46) | LMNAL3MBTL1TDP1AKR1B1KDM4E | |
| SCHEMBL342904 | 0.94 | LMNA (0.46) | LMNAL3MBTL1TDP1AKR1B1KDM4E | |
| SCHEMBL2316246 | 0.94 | LMNA (0.46) | LMNAL3MBTL1TDP1AKR1B1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011500014-A | — | — | 2011-01-06 | — | — | JP | claimed |
| EP-2197488-A1 | IMMUNE STIMULATORY OLIGONUCLEOTIDE ANALOGS CONTAINING MODIFIED SUGAR MOIETIES | Coley Pharmaceuticals GmbH (DE) | 2010-06-23 | — | — | EP | claimed |
| WO-2009047610-A1 | IMMUNE STIMULATORY OLIGONUCLEOTIDE ANALOGS CONTAINING MODIFIED SUGAR MOIETIES | COLEY PHARMACEUTICAL GMBH (DE) | 2009-04-16 | — | — | WO | claimed |
| EP-2197488-A1 | IMMUNE STIMULATORY OLIGONUCLEOTIDE ANALOGS CONTAINING MODIFIED SUGAR MOIETIES | Coley Pharmaceuticals GmbH (DE) | 2010-06-23 | — | — | EP | disclosed |
| WO-2009047610-A1 | IMMUNE STIMULATORY OLIGONUCLEOTIDE ANALOGS CONTAINING MODIFIED SUGAR MOIETIES | COLEY PHARMACEUTICAL GMBH (DE) | 2009-04-16 | — | — | WO | disclosed |
| EP-1942945-A2 | IMMUNOSTIMULATORY PROPERTIES OF OLIGONUCLEOTIDE-BASED COMPOUNDS COMPRISING MODIFIED IMMUNOSTIMULATORY DINUCLEOTIDES | Idera Pharmaceuticals (US) | 2008-07-16 | — | — | EP | disclosed |
| EP-1904077-A1 | METHOD FOR MODULATING RESPONSIVENESS TO STEROIDS | Index Pharmaceuticals AB (SE) | 2008-04-02 | — | — | EP | disclosed |
| EP-1901759-A1 | IMMUNOSTIMULATORY METHOD | Index Pharmaceuticals AB (SE) | 2008-03-26 | — | — | EP | disclosed |
| WO-2007055704-A2 | IMMUNOSTIMULATORY PROPERTIES OF OLIGONUCLEOTIDE-BASED COMPOUNDS COMPRISING MODIFIED IMMUNOSTIMULATORY DINUCLEOTIDES | IDERA PHARMACEUTICALS (US) | 2007-05-18 | — | — | WO | disclosed |
| WO-2007004977-A1 | IMMUNOSTIMULATORY METHOD | INDEX PHARMACEUTICALS AB (SE) | 2007-01-11 | — | — | WO | disclosed |
| WO-2007004979-A1 | METHOD FOR MODULATING RESPONSIVENESS TO STEROIDS | INDEX PHARMACEUTICALS AB (SE) | 2007-01-11 | — | — | WO | disclosed |
| US-6395868-B1 | POLYACETYLENES WITH ESTER, AMINES AND AMIDES COMPOUNDS ARE USEFUL FOR MAKING FILMS WHICH ARE ELECTRICALLY CONDUCTIVE, NEAR INFRARED ABSORBING, POLARIZING, | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2002-05-28 | — | — | US | disclosed |
| US-4394502-A | Immunotherapeutic agent for tumors comprising lipopolysaccharide as an active component | MARUYAMA CHISATO | 1983-07-19 | — | — | US | disclosed |
| US-4329452-A | Immunotherapeutic agent for tumors comprising lipopolysaccharide as an active component | MARUYAMA CHISATO | 1982-05-11 | — | — | US | disclosed |