SCHEMBL2316246

SCHEMBL2316246

CO[C@@H](C=O)[C@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
TDP1 Q9NUW8 1/20 0.44
KDM4E B2RXH2 2/20 0.39
PDE4A P27815 1/20 0.39
USP2 O75604 1/20 0.36
SLCO1B1 Q9Y6L6 1/20 0.36
AKR1B1 P15121 1/20 0.36
TOP1 P11387 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33584 1.00 LMNA (0.46) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL1369560 1.00 LMNA (0.46) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL3130561 1.00 LMNA (0.46) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL4126076 1.00 LMNA (0.46) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL3128140 1.00 LMNA (0.46) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL342904 1.00 LMNA (0.46) LMNAL3MBTL1TDP1KDM4EPDE4A
Ammonia Solution, Strong SCHEMBL16720911 0.98 LMNA (0.44) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL8675811 0.98 TDP1 (0.48) LMNAL3MBTL1TDP1KDM4EPDE4A
Acetic Acid SCHEMBL680584 0.94 PDE4A (0.44) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL616881 0.94 LMNA (0.42) LMNAL3MBTL1TDP1KDM4EPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2150620-B1 Method for preparing C-6 phosphorylated D-aldohexoses and C-6 phosphorylated D-aldohexose derivatives, and new C-6 phosphorylated D-aldohexose derivatives LIBRAGEN (FR) 2011-08-10 EP claimed
EP-2150620-A2 METHOD FOR PREPARING C-6 PHOSPHORYLATED D-ALDOHEXOSES AND C-6 PHOSPHORYLATED D-ALDOHEXOSE DERIVATIVES, AND NEW C-6 PHOSPHORYLATED D-ALDOHEXOSE DERIVATIVES Libragen (FR) 2010-02-10 EP claimed
WO-2008142155-A2 METHOD FOR PREPARING C-6 PHOSPHORYLATED D-ALDOHEXOSES AND C-6 PHOSPHORYLATED D-ALDOHEXOSES DERIVATIVES AND NEW C-6 PHOSPHORYLATED D-ALDOHEXOSES DERIVATIVES LIBRAGEN (FR) 2008-11-27 WO claimed
EP-1995323-A1 Method for preparing C-6 phosphorylated D-aldohexoses and C-6 phosphorylated D-aldohexose derivatives Libragen (FR) 2008-11-26 EP claimed
EP-2864343-B1 SELECTIVE OXIDATION OF CARBOHYDRATES UNIV GRONINGEN (NL) 2017-09-27 EP disclosed
US-9751906-B2 Selective oxidation of carbohydrates RIJKSUNIVERSITEIT GRONINGEN (NL) 2017-09-05 US disclosed
US-20150218196-A1 SELECTIVE OXIDATION OF CARBOHYDRATES RIJKSUNIVERSITEIT GRONINGEN (NL) 2015-08-06 US disclosed
EP-2150620-B1 Method for preparing C-6 phosphorylated D-aldohexoses and C-6 phosphorylated D-aldohexose derivatives, and new C-6 phosphorylated D-aldohexose derivatives LIBRAGEN (FR) 2011-08-10 EP disclosed
EP-2150620-A2 METHOD FOR PREPARING C-6 PHOSPHORYLATED D-ALDOHEXOSES AND C-6 PHOSPHORYLATED D-ALDOHEXOSE DERIVATIVES, AND NEW C-6 PHOSPHORYLATED D-ALDOHEXOSE DERIVATIVES Libragen (FR) 2010-02-10 EP disclosed
WO-2008142155-A2 METHOD FOR PREPARING C-6 PHOSPHORYLATED D-ALDOHEXOSES AND C-6 PHOSPHORYLATED D-ALDOHEXOSES DERIVATIVES AND NEW C-6 PHOSPHORYLATED D-ALDOHEXOSES DERIVATIVES LIBRAGEN (FR) 2008-11-27 WO disclosed
EP-1995323-A1 Method for preparing C-6 phosphorylated D-aldohexoses and C-6 phosphorylated D-aldohexose derivatives Libragen (FR) 2008-11-26 EP disclosed
EP-0033433-A1 Macrolide antibiotics, process for their preparation, inter alia by fermentation, and pharmaceutical compositions containing them SCHERING CORPORATION (US) 1981-08-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150218196-A1 SELECTIVE OXIDATION OF CARBOHYDRATES HAO2, HAO1, HAAO LMNA 4516/4885L3MBTL1 4586/4885TDP1 4305/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.