SCHEMBL10012783

SCHEMBL10012783

COCCOC(=O)CO[Si](C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
DGKA P23743 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
HCAR2 Q8TDS4 1/20 0.33
ADRA2A P08913 1/20 0.31
ADRA1A P35348 1/20 0.31
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
BLM P54132 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9936704 0.81 TSHR (0.43) TSHRDGKASMN1; SMN2HCAR2ADRA2A
SCHEMBL10011308 0.80 HCAR2 (0.42) TSHRDGKAHCAR2ALDH1A1
SCHEMBL12050130 0.79 TSHR (0.42) TSHRDGKASMN1; SMN2HCAR2ADRA2A
SCHEMBL10011568 0.79 ALDH1A1 (0.52) TSHRDGKASMN1; SMN2ALDH1A1
SCHEMBL9275566 0.77 TSHR (0.41) TSHRDGKASMN1; SMN2ADRA2AADRA1A
SCHEMBL10011059 0.77 ATM (0.52) TSHRDGKAHCAR2ALDH1A1
SCHEMBL20862160 0.76 TSHR (0.39) TSHRDGKASMN1; SMN2ADRA2AADRA1A
SCHEMBL15108347 0.76 TSHR (0.39) TSHRDGKASMN1; SMN2HCAR2ADRA2A
SCHEMBL13313904 0.76 TSHR (0.39) TSHRDGKASMN1; SMN2ADRA2AADRA1A
SCHEMBL16285424 0.76 ALDH1A1 (0.41) TSHRDGKASMN1; SMN2ADRA2AADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9130244-B2 Nonaqueous electrolyte solution and electrochemical element using same UBE INDUSTRIES, LTD. (JP) 2015-09-08 US disclosed
EP-2908376-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL ELEMENT USING SAME Ube Industries, Ltd. (JP) 2015-08-19 EP disclosed
EP-2479831-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL ELEMENT USING SAME Ube Industries, Ltd. (JP) 2012-07-25 EP disclosed
US-20120171581-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL ELEMENT USING SAME UBE INDUSTRIES, LTD. (JP) 2012-07-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120171581-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL ELEMENT USING SAME SLC8A1, OR10J3, SLC8B1 TSHR 3669/4885DGKA 1127/4885SMN1; SMN2 4063/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.