SCHEMBL10012959

SCHEMBL10012959

CC(C)c1ccc(N(C=O)c2ccc(C(C)C)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.52
CYP2C9 P11712 3/20 0.38
KDM4E B2RXH2 1/20 0.38
MAPK1 P28482 1/20 0.38
MGLL Q99685 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CYP2D6 P10635 1/20 0.35
HIF1A Q16665 1/20 0.35
HTT P42858 1/20 0.34
PIM1 P11309 1/20 0.34
POLB P06746 1/20 0.34
EGFR P00533 1/20 0.34
ERBB2 P04626 1/20 0.34
USP2 O75604 1/20 0.34
GAA P10253 1/20 0.34
HSD17B10 Q99714 1/20 0.34
USP5 P45974 1/20 0.33
SIRT2 Q8IXJ6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6333507 0.77 NPC1 (0.44) TYRALDH1A1LMNASMN1; SMN2PIM1
SCHEMBL446001 0.76 TYR (0.39) TYRALDH1A1LMNASMN1; SMN2POLB
SCHEMBL6553745 0.73 CYP2A6 (0.58) MAPK1ALDH1A1LMNASMN1; SMN2HIF1A
SCHEMBL2007458 0.73 ALDH1A1 (0.48) ALDH1A1LMNASMN1; SMN2HTTPOLB
SCHEMBL3096128 0.73 HSD17B10 (0.46) KDM4EMAPK1ALDH1A1LMNASMN1; SMN2
SCHEMBL13392612 0.73 ALDH1A1 (0.46) CYP2C9KDM4EMAPK1ALDH1A1LMNA
SCHEMBL3340608 0.72 TYR (0.76) TYRKDM4EMAPK1ALDH1A1LMNA
SCHEMBL18805967 0.72 TYR (0.44) TYRCYP2C9KDM4EMAPK1MGLL
SCHEMBL12922764 0.72 TYR (0.44) TYRCYP2C9KDM4EMAPK1MGLL
Formamide SCHEMBL29161087 0.72 TYR (0.64) TYRCYP2C9KDM4EMAPK1MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2478981-B1 SILVER-(CONJUGATED COMPOUND) COMPLEX SUMITOMO CHEMICAL CO (JP) 2020-12-23 EP disclosed
US-9704612-B2 Composition of silver-conjugated compound composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-11 US disclosed
US-9412487-B2 Silver-(conjugated compound) composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-08-09 US disclosed
US-20140001422-A1 COMPOSITION OF SILVER-CONJUGATED COMPOUND COMPOSITE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-02 US disclosed
EP-2478981-A1 SILVER-(CONJUGATED COMPOUND) COMPLEX Sumitomo Chemical Co., Ltd (JP) 2012-07-25 EP disclosed
US-20120168693-A1 SILVER-(CONJUGATED COMPOUND) COMPOSITE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-05 US disclosed