SCHEMBL2007458

SCHEMBL2007458

Cc1ccc(N(C=O)c2ccc(C)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.48
TSHR P16473 1/20 0.48
CYP2A6 P11509 2/20 0.46
TDP1 Q9NUW8 2/20 0.42
ACHE P22303 1/20 0.42
MAPT P10636 1/20 0.40
MCOLN3 Q8TDD5 1/20 0.40
PKM P14618 2/20 0.36
HTT P42858 2/20 0.36
ATM Q13315 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
LMNA P02545 2/20 0.36
HPGD P15428 1/20 0.36
NLRP1 Q9C000 1/20 0.36
TLR9 Q9NR96 1/20 0.36
MEN1 O00255 1/20 0.36
NTSR1 P30989 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CYP2A13 Q16696 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL172583 0.91 CA12 (0.44) ALDH1A1TSHRCYP2A6ACHEMAPT
SCHEMBL5391604 0.80 HDAC6 (0.67) ALDH1A1HTTHPGDGAARAB9A
SCHEMBL6553745 0.79 CYP2A6 (0.58) ALDH1A1TSHRCYP2A6TDP1MAPT
SCHEMBL9597657 0.79 ALDH1A1 (0.48) ALDH1A1TSHRCYP2A6TDP1ACHE
SCHEMBL2091673 0.77 ALDH1A1 (0.52) ALDH1A1TSHRCYP2A6TDP1ACHE
SCHEMBL6228555 0.77 TDP1 (0.36) ALDH1A1TSHRCYP2A6TDP1ACHE
SCHEMBL3813443 0.75 ALDH1A1 (0.44) ALDH1A1TSHRCYP2A6TDP1ACHE
SCHEMBL14471512 0.75 MAPT (0.31) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
P-Xylene SCHEMBL4351291 0.75 TSHR (0.56) ALDH1A1TSHRCYP2A6TDP1ACHE
SCHEMBL3091401 0.74 CYP2A6 (0.42) ALDH1A1CYP2A6TDP1MAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100237770-A1 GOLD COMPLEX AND PROCESS FOR PREPARING THE SAME, AND ORGANIC ULTRAVIOLET ELECTROLUMINESCENT DEVICE USING SAID GOLD COMPLEX UBE INDUSTRIES, LTD. (JP) 2010-09-23 US claimed
EP-2088151-A1 GOLD COMPLEX, METHOD FOR PRODUCTION OF THE GOLD COMPLEX, AND ORGANIC ULTRAVIOLET ELECTROLUMINESCENT ELEMENT USING THE GOLD COMPLEX Ube Industries, Ltd. (JP) 2009-08-12 EP claimed
EP-2478981-B1 SILVER-(CONJUGATED COMPOUND) COMPLEX SUMITOMO CHEMICAL CO (JP) 2020-12-23 EP disclosed
US-9704612-B2 Composition of silver-conjugated compound composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-11 US disclosed
US-9412487-B2 Silver-(conjugated compound) composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-08-09 US disclosed
US-8729277-B2 Processes for the synthesis of gamma nitrocarbonyl and gamma dicarbonyl compounds and their pyrrole derivatives CHEVRON PHILIPS CHEMICAL COMPANY LP (US) 2014-05-20 US disclosed
US-20140001422-A1 COMPOSITION OF SILVER-CONJUGATED COMPOUND COMPOSITE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-02 US disclosed
EP-2543437-A2 HOMOGENEOUS ASYMMETRIC HYDROGENATION CATALYST Takasago International Corporation (JP) 2013-01-09 EP disclosed
EP-2478981-A1 SILVER-(CONJUGATED COMPOUND) COMPLEX Sumitomo Chemical Co., Ltd (JP) 2012-07-25 EP disclosed
US-20120168693-A1 SILVER-(CONJUGATED COMPOUND) COMPOSITE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-05 US disclosed
US-20120157692-A1 Processes for the Synthesis of Gamma Nitrocarbonyl and Gamma Dicarbonyl Compounds and Their Pyrrole Derivatives CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2012-06-21 US disclosed
US-4822883-A 2,2,6,6-TETRA SUBSTITUTED PIPERIDIN-4-YL PEROXY DERIVATIVES BECOMING CHEMICALLY BONDED TO ADDITION POLYMER PENNWALT CORPORATION (US) 1989-04-18 US disclosed
WO-1989001474-A1 PEROXIDE FREE RADICAL INITIATORS CONTAINING HINDERED AMINE LIGHT STABILIZER GROUPS PENNWALT CORPORATION (US) 1989-02-23 WO disclosed
EP-0294818-A2 Hindered amine light stabilizers containing aromatic carboxy groups and derivatives ELF ATOCHEM NORTH AMERICA, INC. (US) 1988-12-14 EP disclosed
US-4382934-A ANTIALLERGENS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-05-10 US disclosed
EP-0010398-B1 ISATIN DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-04-27 EP disclosed
US-RE30752-E CHEMICAL REACTANT FOR PROTECTING AMINO OR IMINO GROUPS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-09-29 US disclosed
EP-0010398-A1 Isatin derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-04-30 EP disclosed
US-4074057-A HYPERLIPEMIA, DIABETES TAKEDA CHEMICAL CO., LTD. (JA) 1978-02-14 US disclosed
US-4010178-A Carbonic acid esters, and the preparation thereof and their use FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1977-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100237770-A1 GOLD COMPLEX AND PROCESS FOR PREPARING THE SAME, AND ORGANIC ULTRAVIOLET ELECTROLUMINESCENT DEVICE USING SAID GOLD COMPLEX APOL1, UFL1, ACSL3 ALDH1A1 435/4885TSHR 2791/4885CYP2A6 2437/4885
US-20120157692-A1 Processes for the Synthesis of Gamma Nitrocarbonyl and Gamma Dicarbonyl Compounds and Their Pyrrole Derivatives DHPS, DNPH1, DDT ALDH1A1 2354/4885TSHR 4744/4885CYP2A6 2375/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.