⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22859888 | 0.83 | L3MBTL1 (0.35) | — | |
| SCHEMBL2686953 | 0.79 | L3MBTL1 (0.31) | — | |
| SCHEMBL15499249 | 0.78 | — | — | |
| SCHEMBL25490411 | 0.77 | — | — | |
| SCHEMBL27368572 | 0.76 | ALDH1A1 (0.34) | — | |
| SCHEMBL13403077 | 0.74 | ANPEP (0.36) | — | |
| SCHEMBL12233444 | 0.74 | TDP1 (0.33) | — | |
| SCHEMBL25129792 | 0.73 | — | — | |
| SCHEMBL25490665 | 0.73 | ANPEP (0.30) | — | |
| SCHEMBL3509058 | 0.73 | CYP2D6 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023098889-A1 | ANTI-HUMAN TROP2 ANTIBODY-CAMPTOTHECIN DRUG CONJUGATE AND MEDICAL USE THEREOF | 成都百利多特生物药业有限责任公司 | 2023-06-08 | — | — | WO | disclosed |
| WO-2023083381-A1 | BISPECIFIC ANTIBODY-CAMPTOTHECIN DRUG CONJUGATE AND PHARMACEUTICAL USE THEREOF | 成都百利多特生物药业有限责任公司 | 2023-05-19 | — | — | WO | disclosed |
| US-9052298-B2 | High density plate filler | APPLIED BIOSYSTEMS, LLC (US) | 2015-06-09 | — | — | US | disclosed |
| US-8638509-B2 | Optical camera alignment | APPLIED BIOSYSTEMS, LLC (US) | 2014-01-28 | — | — | US | disclosed |
| US-20130210674-A1 | WHOLE GENOME EXPRESSION ANALYSIS SYSTEM | Life Technologies Corporation (US) | 2013-08-15 | — | — | US | disclosed |
| US-20120080610-A1 | OPTICAL CAMERA ALIGNMENT | Life Technologies Corporation (US) | 2012-04-05 | — | — | US | disclosed |
| US-20110220239-A1 | HIGH DENSITY PLATE FILLER | Life Technologies Corporation (US) | 2011-09-15 | — | — | US | disclosed |
| US-20070138294-A1 | Method of reading code symbols using a hand-supportable digital image capturing and processing device employing a micro-computing platform supporting an event-driven multi-tier modular software architecture | METROLOGIC INSTRUMENTS, INC. (US) | 2007-06-21 | — | — | US | disclosed |