SCHEMBL1001349

SCHEMBL1001349

CCCCSCCCC.[Rh]

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.43
LMNA P02545 2/20 0.43
CES1 P23141 5/20 0.42
CES2 O00748 3/20 0.40
THRB P10828 2/20 0.40
MAPT P10636 2/20 0.40
GMNN O75496 1/20 0.40
TP53 P04637 1/20 0.40
POLB P06746 1/20 0.40
CYP2C9 P11712 1/20 0.40
BLM P54132 1/20 0.40
HSD17B10 Q99714 1/20 0.40
NOS3 P29474 1/20 0.39
NOS1 P29475 1/20 0.39
NOS2 P35228 1/20 0.39
CA2 P00918 1/20 0.39
GBA1 P04062 1/20 0.36
ATM Q13315 1/20 0.36
FAAH O00519 4/20 0.34
PLA2G6 O60733 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4849581 1.00 TSHR (0.43) TSHRLMNACES1CES2THRB
Hydrochloric Acid SCHEMBL4946144 0.96 CES1 (0.41) TSHRLMNACES1CES2THRB
Hydrochloric Acid SCHEMBL1000866 0.96 CES1 (0.41) TSHRLMNACES1CES2THRB
SCHEMBL21882 0.96
SCHEMBL11527395 0.92 TSHR (0.43) TSHRLMNACES1CES2THRB
SCHEMBL747847 0.92 TSHR (0.43) TSHRLMNACES1CES2THRB
Iodide SCHEMBL7869089 0.92 TSHR (0.43) TSHRLMNACES1CES2THRB
SCHEMBL1406213 0.92 CES2 (0.46) TSHRLMNACES1CES2THRB
SCHEMBL10591515 0.92 TSHR (0.43) TSHRLMNACES1CES2THRB
SCHEMBL6689804 0.92 TSHR (0.43) TSHRLMNACES1CES2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1772501-B1 Silicone-coated architectural glass IND CONTROL DEV INC (US) 2015-08-12 EP claimed
CN-1939858-B Silicone-coated architectural glass IND CONTROL DEV INC 2012-03-14 CN claimed
US-7838116-B2 Silicone-coated architectural and decorative glass INDUSTRIAL CONTROL DEVELOPMENT, INC. (US) 2010-11-23 US claimed
US-7605219-B2 Selective hydrosilylation method with alcohol or epoxide reactant and product MOMENTIVE PERFORMANCE MATERIALS (US) 2009-10-20 US claimed
US-20090202842-A1 Silicone-coated architectural & decorative glass INDUSTRIAL CONTROL DEVELOPMENT, INC. 2009-08-13 US claimed
US-7531242-B2 Silicone-coated architectural glass INDUSTRIAL CONTROL DEVELOPMENT, INC. (US) 2009-05-12 US claimed
US-20080081924-A1 SELECTIVE MOLAR EXCESS HYDROSILYLATION METHOD AND PRODUCT MOMENTIVE PERFORMANCE MATERIALS INC. 2008-04-03 US claimed
US-20080076894-A1 SELECTIVE HYDROSILYLATION METHOD WITH ALCOHOL OR EPOXIDE REACTANT AND PRODUCT MOMENTIVE PERFORMANCE MATERIALS INC. 2008-03-27 US claimed
US-20080033136-A1 SELECTIVE HYDROSILYLATION CONDITIONS MOMENTIVE PERFORMANCE MATERIALS INC. 2008-02-07 US claimed
US-20080015323-A1 SELECTIVE HYDROSILYLATION METHOD AND PRODUCT MOMENTIVE PERFORMANCE MATERIALS INC. 2008-01-17 US claimed
US-20080015325-A1 SELECTIVE HYDROSILYLATION METHOD AND PRODUCT MOMENTIVE PERFORMANCE MATERIALS INC. 2008-01-17 US claimed
US-20080015324-A1 Use of tris(dibutylsulfide)rhodium trichloride catalyst to make a siloxane-functional polyoxyalkylene glycol; use as a hydrolysis resistant-imparting agent for a composition in need of hydrolysis resistance such as agrochemical, personal care, and home care formulations MOMENTIVE PERFORMANCE MATERIALS INC. 2008-01-17 US claimed
US-20070078337-A1 Silicone-coated architectural glass INDUSTRIAL CONTROL DEVELOPMENT, INC. 2007-04-05 US claimed
CN-1939858-A Silicone-coated architectural glass IND CONTROL DEV INC (US) 2007-04-04 CN claimed
US-8217129-B2 Polyalkylene oxide asymmetric siloxane MOMENTIVE PERFORMANCE MATERIALS (US) 2012-07-10 US disclosed
CN-101346405-B Solvent resistant polyurethane adhesive compositions MOMENTIVE PERFORMANCE MAT INC 2012-03-28 CN disclosed
CN-1939858-B Silicone-coated architectural glass IND CONTROL DEV INC 2012-03-14 CN disclosed
US-20070078337-A1 Silicone-coated architectural glass INDUSTRIAL CONTROL DEVELOPMENT, INC. 2007-04-05 US disclosed
CN-1939858-A Silicone-coated architectural glass IND CONTROL DEV INC (US) 2007-04-04 CN disclosed
CN-1809619-A Curable silicone compositions with improved adhesion to polymeric films GEN ELECTRIC (US) 2006-07-26 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080081924-A1 SELECTIVE MOLAR EXCESS HYDROSILYLATION METHOD AND PRODUCT HRH3, HRH4, B2M TSHR 3226/4885LMNA 4082/4885CES1 4020/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.