SCHEMBL10013591

SCHEMBL10013591

C=CP(=O)(C=C)Oc1ccc(-c2ccc(OP(=O)(C=C)C=C)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.37
CYP3A4 P08684 1/20 0.37
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
DRD1 P21728 1/20 0.34
SRC P12931 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
ALOX15 P16050 1/20 0.30
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7768590 0.93 TSHR (0.41) TSHRCYP3A4MEN1KMT2ASRC
SCHEMBL2735763 0.86 TSHR (0.42) TSHRCYP3A4MEN1KMT2ASRC
SCHEMBL13002790 0.86 HPGD (0.32) PKM
SCHEMBL2735767 0.84 BLM (0.33) TSHRCYP3A4L3MBTL1
SCHEMBL781472 0.82 SRC (0.52) TSHRMEN1KMT2ASRCTDP1
SCHEMBL2735717 0.81 PTPN1 (0.40) TSHRCYP3A4MEN1KMT2AALOX15
SCHEMBL2735764 0.80 GPR84 (0.46) TSHRCYP3A4MEN1KMT2ASRC
SCHEMBL2735740 0.78 ALDH1A1 (0.39) TSHRCYP3A4MEN1KMT2APKM
SCHEMBL7768594 0.76 SRC (0.43) TSHRMEN1KMT2ASRCTDP1
SCHEMBL2735766 0.75 SRC (0.45) TSHRMEN1KMT2ASRCTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8115134-B2 Arc extinguishing resin processed article and circuit breaker using the same FUJI ELECTRIC FA COMPONENTS & SYSTEMS CO., LTD. (JP) 2012-02-14 US disclosed
US-20090283500-A1 ARC EXTINGUISHING RESIN PROCESSED ARTICLE AND CIRCUIT BREAKER USING THE SAME FUJI ELECTRIC FA COMPONENTS & SYSTEMS CO., LTD. (JP) 2009-11-19 US disclosed