Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TLR2 | O60603 | 1/20 | 0.35 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.35 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17428937 | 0.85 | MEN1 (0.42) | ALDH1A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL15653257 | 0.82 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL8834700 | 0.80 | TAAR1 (0.47) | ALDH1A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL1486001 | 0.80 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL16960352 | 0.80 | AKR1B1 (0.39) | ALDH1A1KMT2ALMNAAKR1B1SMN1; SMN2 | |
| SCHEMBL15654617 | 0.80 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL15824333 | 0.80 | KMT2A (0.45) | ALDH1A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL15100314 | 0.80 | TAAR1 (0.38) | ALDH1A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL14760961 | 0.80 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL10013774 | 0.79 | MEN1 (0.41) | ALDH1A1MEN1KMT2ATDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159529-A1 | AROMATIC COMPOUND AND APPLICATION THEREOF IN ANTITUMOR DRUG | SHANGHAI ZHEYE BIOTECHNOLOGY CO., LTD. (CN) | 2023-05-25 | — | — | US | disclosed |
| US-8168833-B2 | Schwartz reagents: methods of in situ generation and use | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2012-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159529-A1 | AROMATIC COMPOUND AND APPLICATION THEREOF IN ANTITUMOR DRUG | TYR, APC, TP53 | ALDH1A1 3494/4885MEN1 3762/4885KMT2A 2815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.