SCHEMBL1001384

SCHEMBL1001384

[CH2]CCC(=O)OC(C)CC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.39
EPHX2 P34913 1/20 0.39
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA3 P07451 1/20 0.38
CA4 P22748 1/20 0.38
CA6 P23280 1/20 0.38
CA5A P35218 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CA13 Q8N1Q1 1/20 0.38
CA14 Q9ULX7 1/20 0.38
CA5B Q9Y2D0 1/20 0.38
MAPT P10636 2/20 0.33
MAPK1 P28482 1/20 0.33
FAAH O00519 4/20 0.32
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
ALDH1A1 P00352 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2805336 0.88 LMNA (0.46) LMNAEPHX2CA12CA1CA2
SCHEMBL645070 0.86 CA12 (0.45) LMNAEPHX2CA12CA1CA2
SCHEMBL7603513 0.86 LMNA (0.48) LMNAEPHX2CA12CA1CA2
SCHEMBL7609993 0.84 LMNA (0.52) LMNAEPHX2MAPTMAPK1ALDH1A1
SCHEMBL6231000 0.82 LMNA (0.52) LMNAEPHX2CA12CA1CA2
SCHEMBL2980900 0.82 ALDH1A1 (0.50) LMNAEPHX2CA12CA1CA2
SCHEMBL1585214 0.82 ALDH1A1 (0.50) LMNAEPHX2CA12CA1CA2
SCHEMBL10554751 0.82 LMNA (0.57) LMNAEPHX2CA12CA1CA2
SCHEMBL2989645 0.82 ALDH1A1 (0.50) LMNAEPHX2CA12CA1CA2
SCHEMBL1001142 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0951467-B1 SUBSTITUTED NITROGEN CONTAINING HETEROCYCLES AS INHIBITORS OF p38 PROTEIN KINASE VERTEX PHARMA (US) 2003-04-02 EP claimed
EP-2277597-B2 Reductive colour removal HENKEL AG & CO KGAA (DE) 2024-06-26 EP disclosed
WO-2023176458-A1 DISINFECTING COMPOSITION CONTAINING THIAZOLE CARBOXYLIC ACID HYDRAZIDE COMPOUND 石原産業株式会社 2023-09-21 WO disclosed
EP-2277599-B1 Reductive colour removal HENKEL AG & CO KGAA (DE) 2019-01-23 EP disclosed
EP-2277598-B1 Reductive colour removal HENKEL AG & CO KGAA (DE) 2017-08-02 EP disclosed
US-9045465-B1 3-heterocyclyl-substituted benzoyl derivatives BASF SE (DE) 2015-06-02 US disclosed
EP-2056780-B1 REDUCTIVE COLOUR REMOVAL HENKEL AG & CO KGAA (DE) 2013-08-14 EP disclosed
EP-1613607-B1 BENZENESULPHONAMIDE DERIVATIVES AS HERBICIDES OR DESICCANT/DEFOLIANT COMPOUNDS BASF SE (DE) 2013-01-09 EP disclosed
EP-2277599-A1 Reductive colour removal Henkel AG & Co. KGaA (DE) 2011-01-26 EP disclosed
EP-2277598-A1 Reductive colour removal Henkel AG & Co. KGaA (DE) 2011-01-26 EP disclosed
WO-1998012182-A1 1-SULFONYL-3-PHENYLPYRAZOLES AND THEIR USE AS HERBICIDES AND FOR DESICCATING OR DEFOLIATING PLANTS BASF AKTIENGESELLSCHAFT (DE) 1998-03-26 WO disclosed
WO-1998007720-A1 SUBSTITUTED 2-ARYLPYRIDINE AS HERBICIDE BASF AKTIENGESELLSCHAFT (DE) 1998-02-26 WO disclosed
WO-1997015559-A1 SUBSTITUTED 4,5-DI(TRIFLUOROMETHYL)PYRAZOLES AND THEIR USE AS HERBICIDES AND FOR DESICCATING/DEFOLIATING PLANTS BASF AKTIENGESELLSCHAFT (DE) 1997-05-01 WO disclosed
WO-1997011059-A1 SUBSTITUTED 2-PHENYLPYRIDINES AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1997-03-27 WO disclosed
EP-0721454-A1 NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST J. URIACH & CIA. S.A. (ES) 1996-07-17 EP disclosed
US-5318968-A Antithrombotic agents; cardiotonic agents; vasodilators NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1994-06-07 US disclosed
US-5314883-A Vasodilation, anticoagulants NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1994-05-24 US disclosed
US-5202323-A Antithrombotic, inotropic, vasodilator, antiallergen NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1993-04-13 US disclosed
EP-0482208-A1 PYRIDAZINONE DERIVATIVE NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1992-04-29 EP disclosed
US-4289883-A ADRENERGIC BLOCKING AGENTS OF EXCELLENT CARDIOSELECTIVITY OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1981-09-15 US disclosed