Clodinafop Propargyl

Clodinafop Propargyl

SCHEMBL10014176

C#CCOC(=O)[C@H](C)Oc1ccc(Oc2ncc(Cl)cc2F)cc1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.57
LTA4H P09960 9/20 0.44
KCNH2 Q12809 5/20 0.44
MEN1 O00255 1/20 0.42
MAPT P10636 1/20 0.42
KMT2A Q03164 1/20 0.42
GAA P10253 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
PTGER4 P35408 2/20 0.40
PTGER2 P43116 1/20 0.40
PPARG P37231 1/20 0.40
LMNA P02545 1/20 0.39
CYP2C9 P11712 1/20 0.39
TSHR P16473 1/20 0.39
APEX1 P27695 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
LIPE Q05469 1/20 0.39
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Clodinafop Propargyl SCHEMBL63886 1.00 L3MBTL1 (0.57) L3MBTL1LTA4HKCNH2MEN1MAPT
Clodinafop Propargyl SCHEMBL29375181 1.00 L3MBTL1 (0.57) L3MBTL1LTA4HKCNH2MEN1MAPT
Clodinafop Propargyl SCHEMBL63885 1.00 L3MBTL1 (0.57) L3MBTL1LTA4HKCNH2MEN1MAPT
Clodinafop Propargyl SCHEMBL28325546 1.00 L3MBTL1 (0.57) L3MBTL1LTA4HKCNH2MEN1MAPT
Clodinafop Propargyl SCHEMBL28237151 0.99 L3MBTL1 (0.56) L3MBTL1LTA4HKCNH2MEN1MAPT
Clodinafop Propargyl SCHEMBL187142 0.96 L3MBTL1 (0.53) L3MBTL1LTA4HKCNH2MEN1MAPT
Clodinafop Propargyl SCHEMBL8854799 0.95 L3MBTL1 (0.55) L3MBTL1LTA4HKCNH2MEN1MAPT
Clodinafop Propargyl SCHEMBL15546128 0.93 L3MBTL1 (0.51) L3MBTL1LTA4HKCNH2GAATDP1
SCHEMBL8332894 0.90 L3MBTL1 (0.69) L3MBTL1MEN1MAPTKMT2AGAA
SCHEMBL30939017 0.90 L3MBTL1 (0.69) L3MBTL1MEN1MAPTKMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012003748-A1 N-OXO-ARYLOXYPHENOXYCARBOXYLIC ACID AMIDE COMPOUNDS WITH BIOLOGICAL ACTIVITIES, PREPARATION METHOD AND APPLICATION THEREOF 湖南化工研究院 (CN) 2012-01-12 WO disclosed