Clodinafop Propargyl

Clodinafop Propargyl

SCHEMBL187142

C#CCOC(=O)[C@@H](C)Oc1ccc(Oc2ncc(Cl)cc2F)cc1.C[C@@H](Oc1ccc(Oc2ncc(Cl)cc2F)cc1)C(=O)O

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.53
LTA4H P09960 9/20 0.43
KCNH2 Q12809 5/20 0.43
MAP4K4 O95819 2/20 0.40
PTGER4 P35408 2/20 0.40
PPARG P37231 2/20 0.40
PTGER2 P43116 1/20 0.40
GAA P10253 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
MEN1 O00255 1/20 0.39
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Clodinafop Propargyl SCHEMBL15546128 0.97 L3MBTL1 (0.51) L3MBTL1LTA4HKCNH2MAP4K4PTGER4
Clodinafop Propargyl SCHEMBL63886 0.96 L3MBTL1 (0.57) L3MBTL1LTA4HKCNH2PTGER4PPARG
Clodinafop Propargyl SCHEMBL28325546 0.96 L3MBTL1 (0.57) L3MBTL1LTA4HKCNH2PTGER4PPARG
Clodinafop Propargyl SCHEMBL10014176 0.96 L3MBTL1 (0.57) L3MBTL1LTA4HKCNH2PTGER4PPARG
Clodinafop Propargyl SCHEMBL29375181 0.96 L3MBTL1 (0.57) L3MBTL1LTA4HKCNH2PTGER4PPARG
Clodinafop Propargyl SCHEMBL63885 0.96 L3MBTL1 (0.57) L3MBTL1LTA4HKCNH2PTGER4PPARG
Clodinafop Propargyl SCHEMBL28237151 0.95 L3MBTL1 (0.56) L3MBTL1LTA4HKCNH2PTGER4PPARG
Clodinafop Propargyl SCHEMBL8854799 0.93 L3MBTL1 (0.55) L3MBTL1LTA4HKCNH2PTGER4PPARG
Clodinafop SCHEMBL1535846 0.89 L3MBTL1 (0.53) L3MBTL1LTA4HKCNH2MAP4K4PTGER4
Clodinafop SCHEMBL15289880 0.89 L3MBTL1 (0.53) L3MBTL1LTA4HKCNH2MAP4K4PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3758488-A1 FATTY ACID DERIVATIVES FOR USE AS HERBICIDES Clariant International Ltd (CH) 2021-01-06 EP disclosed
US-20200404909-A1 Fatty acid derivatives for use as herbicides CLARIANT INTERNATIONAL LTD. (CH) 2020-12-31 US disclosed
WO-2019162484-A1 FATTY ACID DERIVATIVES FOR USE AS HERBICIDES CLARIANT INTERNATIONAL LTD (CH) 2019-08-29 WO disclosed
US-10159249-B2 Use of 2-chloro-3-(methylsulfanyl)-N-(1-methyl-1H-tetrazol-5-yl)-4-(trifluoromethyl)benzamide or its salts for controlling unwanted plants in areas of transgenic crop plants being tolerant to HPPD inhibitor herbicides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-12-25 US disclosed
EP-2534133-B1 BIPHENYL SUBSTITUTED CYCLICAL KETO-ENOLS BAYER CROPSCIENCE AG (DE) 2018-09-05 EP disclosed
EP-2516632-B1 PLANTS TOLERANT TO HPPD INHIBITOR HERBICIDES BAYER IP GMBH (DE) 2018-02-14 EP disclosed
EP-2516631-B1 PLANTS TOLERANT TO HPPD INHIBITOR HERBICIDES BAYER IP GMBH (DE) 2018-02-14 EP disclosed
EP-2516635-B1 PLANTS TOLERANT TO HPPD INHIBITOR HERBICIDES BAYER IP GMBH (DE) 2017-11-15 EP disclosed
EP-2516633-B1 PLANTS TOLERANT TO HPPD INHIBITOR HERBICIDES BAYER IP GMBH (DE) 2017-11-15 EP disclosed
EP-2516630-B1 PLANTS TOLERANT TO HPPD INHIBITOR HERBICIDES BAYER IP GMBH (DE) 2017-11-15 EP disclosed
WO-2009129953-A1 2-(BENZYLSULFONYL)-OXAZOLE DERIVATIVES, CHIRAL 2- (BENZYLSULFINYL) -OXAZOLE DERIVATIVES AND 2-(BENZYLSULFANYL)-OXAZOLE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF, AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS BAYER CROPSCIENCE AG (DE) 2009-10-29 WO disclosed
WO-2009129954-A2 2-[(1H-PYRAZOLE-4-YLMETHYL)-SULFONYL]-OXAZOLE DERIVATIVES, 2-[(1H-PYRAZOLE-4-YLMETHYL)-SULFANYL]-OXAZOLE DERIVATIVES, AND CHIRAL 2-[(1H-PYRAZOLE-4-YLMETHYL)-SULFINYL]-OXAZOLE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF, AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS BAYER CROPSCIENCE AG (DE) 2009-10-29 WO disclosed
EP-2112149-A1 2-[(1H-Pyrazol-4-ylmethyl)-sulfonyl]-oxazole derivatives, 2-[(1H-pyrazol-4-ylmethyl)-sulfanyl]-oxazole derivatives and chiral 2-[(1H-pyrazol-4-ylmethyl)-sulfinyl]-oxazole derivatives, method for production of same and their use as herbicides and plant growth regulators Bayer CropScience Aktiengesellschaft (DE) 2009-10-28 EP disclosed
EP-2112143-A1 2-(benzylsulfonyl)-oxazol-derivatives, chiral 2-(benzylsulfinyl]-oxazol derivatives, 2-(benzylsulfanyl-oxazol) derivatives, process for their preparation, as well as their use as herbicide and plant growth regulators Bayer CropScience AG (DE) 2009-10-28 EP disclosed
WO-2009118125-A1 4-(3-AMINOBENZOYL)-5-CYCLOPROPYLISOXAZOLES EFFECTIVE AS HERBICIDES BAYER CROPSCIENCE AG (DE) 2009-10-01 WO disclosed
EP-2105437-A1 4-(3-Aminobenzoyl)-5-cyclopropylisoxazols as herbicides Bayer CropScience Aktiengesellschaft (DE) 2009-09-30 EP disclosed
US-20090156406-A1 Polymer Composite Film With Biocide Functionality BAYER INNOVATION GMBH (DE) 2009-06-18 US disclosed
WO-2009059712-A2 HOMOGENEOUS AND STORAGE-STABLE MIXTURES OF DIFFERENT ACTIVE PLANT PROTECTION AGENT GRANULE PARTICLES BAYER CROPSCIENCE AG (DE) 2009-05-14 WO disclosed
EP-2057898-A1 Homogeneous, storage-stable mixtures of different granulate particles of plant protection agents Bayer CropScience AG (DE) 2009-05-13 EP disclosed
WO-2009012887-A1 POLYMER COMPOSITE MATERIAL WITH BIOCIDE FUNCTIONALITY BAYER INNOVATION GMBH (DE) 2009-01-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200404909-A1 Fatty acid derivatives for use as herbicides FFAR1, FFAR3, FFAR2 L3MBTL1 859/4885LTA4H 2131/4885KCNH2 3226/4885
US-20090156406-A1 Polymer Composite Film With Biocide Functionality PUF60, PARG, PRR12 L3MBTL1 3979/4885LTA4H 2263/4885KCNH2 1258/4885
US-10159249-B2 Use of 2-chloro-3-(methylsulfanyl)-N-(1-methyl-1H-tetrazol-5-yl)-4-(trifluoromethyl)benzamide or its salts for controlling unwanted plants in areas of transgenic crop plants being tolerant to HPPD inhibitor herbicides HPD, PGD, PHYKPL L3MBTL1 634/4885LTA4H 1844/4885KCNH2 2191/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.