Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | PRKCG | P05129 | 1/20 | 0.35 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | MARK3 | P27448 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18392461 | 0.96 | MMP12 (0.39) | MMP12CHEK1EPHX2L3MBTL1GRIN2B | |
| SCHEMBL18735531 | 0.93 | MMP12 (0.37) | MMP12CHEK1EPHX2L3MBTL1GRIN2B | |
| SCHEMBL18392489 | 0.91 | MMP12 (0.41) | MMP12CHEK1EPHX2L3MBTL1GRIN2B | |
| SCHEMBL19415113 | 0.88 | FFAR4 (0.40) | MMP12CHEK1EPHX2JAK2ROCK2 | |
| SCHEMBL6452622 | 0.88 | CHEK1 (0.36) | MMP12CHEK1EPHX2L3MBTL1GRIN2B | |
| SCHEMBL6452628 | 0.88 | CHEK1 (0.36) | MMP12CHEK1EPHX2L3MBTL1GRIN2B | |
| SCHEMBL16579011 | 0.86 | KDM1A (0.37) | MMP12L3MBTL1GRIN2BNISCHTRPV1 | |
| SCHEMBL7913867 | 0.85 | ALDH1A1 (0.39) | MMP12CHEK1EPHX2TRPV1ESR2 | |
| SCHEMBL16579012 | 0.85 | CYP2C9 (0.38) | MMP12L3MBTL1GRIN2BNISCHTRPV1 | |
| SCHEMBL10014150 | 0.84 | PDE2A (0.37) | EPHX2GRIN2BGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9238775-B2 | Switch element comprising a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2016-01-19 | — | — | US | disclosed |
| US-9222023-B2 | Liquid crystal composition and display device thereof | JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) | 2015-12-29 | — | — | US | disclosed |
| US-20150076405-A1 | LIQUID CRYSTAL COMPOSITION AND DISPLAY DEVICE THEREOF | JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) | 2015-03-19 | — | — | US | disclosed |
| US-20130208227-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2013-08-15 | — | — | US | disclosed |
| WO-2012052100-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2012-04-26 | — | — | WO | disclosed |