Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10311704 | 0.95 | RAB9A (0.35) | PKMNPSR1LMNATP53ESR2 | |
| SCHEMBL9556482 | 0.85 | ESR2 (0.33) | ESR2ATMMEN1KMT2ACYP2C19 | |
| SCHEMBL9556478 | 0.85 | ESR2 (0.33) | ESR2ATMMEN1KMT2ACYP2C19 | |
| SCHEMBL10013942 | 0.82 | KDM1A (0.38) | LMNAMAPTMEN1KMT2A | |
| SCHEMBL21654545 | 0.82 | PKM (0.33) | PKMNPSR1LMNATP53MAPT | |
| SCHEMBL12918619 | 0.81 | MAPT (0.38) | PKMNPSR1LMNATP53MAPT | |
| SCHEMBL12754471 | 0.81 | MAPT (0.38) | PKMNPSR1LMNATP53MAPT | |
| SCHEMBL10640258 | 0.80 | CYP2C9 (0.38) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL10640266 | 0.80 | CYP2C9 (0.38) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL10640260 | 0.80 | CYP2C9 (0.38) | LMNAMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9238775-B2 | Switch element comprising a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2016-01-19 | — | — | US | disclosed |
| US-20130208227-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2013-08-15 | — | — | US | disclosed |
| WO-2012052100-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2012-04-26 | — | — | WO | disclosed |