Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | LIPE | Q05469 | 4/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.38 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.38 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10014178 | 0.90 | L3MBTL1 (0.46) | L3MBTL1LIPEBCHEPTGER4 | |
| SCHEMBL10014382 | 0.88 | LMNA (0.55) | LMNASMN1; SMN2LIPEMEN1MAPT | |
| SCHEMBL9362254 | 0.86 | L3MBTL1 (0.58) | L3MBTL1LMNASMN1; SMN2CYP2C9TSHR | |
| SCHEMBL30939017 | 0.85 | L3MBTL1 (0.69) | L3MBTL1LMNASMN1; SMN2CYP2C9TSHR | |
| SCHEMBL8332894 | 0.85 | L3MBTL1 (0.69) | L3MBTL1LMNASMN1; SMN2CYP2C9TSHR | |
| SCHEMBL9362215 | 0.85 | L3MBTL1 (0.57) | L3MBTL1LMNASMN1; SMN2CYP2C9TSHR | |
| SCHEMBL10014383 | 0.84 | L3MBTL1 (0.56) | L3MBTL1LMNASMN1; SMN2CYP2C9TSHR | |
| SCHEMBL10014379 | 0.83 | L3MBTL1 (0.56) | L3MBTL1LMNASMN1; SMN2CYP2C9TSHR | |
| SCHEMBL9365761 | 0.82 | L3MBTL1 (0.57) | L3MBTL1LMNASMN1; SMN2CYP2C9TSHR | |
| SCHEMBL9849063 | 0.81 | L3MBTL1 (0.55) | L3MBTL1LMNASMN1; SMN2CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012003748-A1 | N-OXO-ARYLOXYPHENOXYCARBOXYLIC ACID AMIDE COMPOUNDS WITH BIOLOGICAL ACTIVITIES, PREPARATION METHOD AND APPLICATION THEREOF | 湖南化工研究院 (CN) | 2012-01-12 | — | — | WO | disclosed |