Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26948272 | 0.76 | ALDH1A1 (0.67) | KMT2AMEN1ALDH1A1SMN1; SMN2CYP2C9 | |
| SCHEMBL31372407 | 0.76 | ALDH1A1 (0.67) | KMT2AMEN1ALDH1A1SMN1; SMN2CYP2C9 | |
| SCHEMBL20464796 | 0.76 | ALDH1A1 (0.67) | KMT2AMEN1ALDH1A1SMN1; SMN2CYP2C9 | |
| SCHEMBL31372514 | 0.76 | ALDH1A1 (0.67) | KMT2AMEN1ALDH1A1SMN1; SMN2CYP2C9 | |
| SCHEMBL521622 | 0.76 | ALDH1A1 (0.67) | KMT2AMEN1ALDH1A1SMN1; SMN2CYP2C9 | |
| SCHEMBL30210159 | 0.73 | ALDH1A1 (0.63) | KMT2AMEN1ALDH1A1SMN1; SMN2CYP2C9 | |
| SCHEMBL9463318 | 0.72 | ALDH1A1 (0.52) | KMT2AALDH1A1SMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL12858738 | 0.71 | ALDH1A1 (0.55) | KMT2AALDH1A1SMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL7603402 | 0.71 | ALDH1A1 (0.55) | KMT2AALDH1A1SMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL22808576 | 0.71 | ALDH1A1 (0.50) | KMT2AALDH1A1SMN1; SMN2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120029161-A1 | COMPOSITION FOR THERMOPLASTIC SILICONE RESIN | NITTO DENKO CORPORATION (JP) | 2012-02-02 | — | — | US | disclosed |
| US-20120029161-A1 | COMPOSITION FOR THERMOPLASTIC SILICONE RESIN | NITTO DENKO CORPORATION (JP) | 2012-02-02 | — | — | US | disclosed |