SCHEMBL10015461

SCHEMBL10015461

CCC(O)COC(=O)C(C)(C)CC(C)(CC)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 2/20 0.33
LMNA P02545 2/20 0.33
PRKCA P17252 1/20 0.33
ADRB2 P07550 2/20 0.30
ADRB1 P08588 2/20 0.30
ADRB3 P13945 2/20 0.30
KDM4E B2RXH2 1/20 0.30
DUSP3 P51452 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
ACACB O00763 1/20 0.30
ACACA Q13085 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14354901 0.91 LMNA (0.40) HMGCRLMNAPRKCAKDM4EDUSP3
SCHEMBL10015478 0.88 LMNA (0.32) HMGCRLMNAPRKCA
SCHEMBL8986670 0.81 HMGCR (0.41) HMGCRLMNAPRKCAADRB2ADRB1
SCHEMBL20100810 0.80 KDM4E (0.39) LMNAPRKCAKDM4EDUSP3MEN1
SCHEMBL14520517 0.80 TDP1 (0.31) LMNAMEN1KMT2AACACBACACA
SCHEMBL10015483 0.79 PRKCA (0.31) PRKCA
SCHEMBL10015477 0.76 ACACB (0.32) LMNAPRKCAACACBACACA
SCHEMBL16786107 0.76 CYP4F2 (0.38)
SCHEMBL2741177 0.75
SCHEMBL11306638 0.74 KDM4E (0.43) LMNAPRKCAADRB2ADRB1ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8728326-B2 Polymer and methods for preparing and using the same GENERAL ELECTRIC COMPANY (US) 2014-05-20 US disclosed
US-20120152851-A1 POLYMER AND METHODS FOR PREPARING AND USING THE SAME BL TECHNOLOGIES, INC. 2012-06-21 US disclosed