SCHEMBL10017002

SCHEMBL10017002

Cc1ccc2cc(-c3c4ccccc4c(-c4ccc(-c5cccnc5-c5ccccn5)c5ccccc45)c4ccccc34)ccc2c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.38
NPC1 O15118 3/20 0.38
TGFBR1 P36897 3/20 0.37
SMN1; SMN2 Q16637 4/20 0.36
NPSR1 Q6W5P4 4/20 0.36
MAPT P10636 4/20 0.36
KMT2A Q03164 3/20 0.36
MCL1 Q07820 2/20 0.36
GAA P10253 2/20 0.36
HTT P42858 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
POLB P06746 1/20 0.36
NPY5R Q15761 2/20 0.36
PKM P14618 4/20 0.36
TP53 P04637 3/20 0.36
ALDH1A1 P00352 2/20 0.36
HSD17B10 Q99714 2/20 0.36
RAB9A P51151 2/20 0.36
HPGD P15428 1/20 0.36
MEN1 O00255 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10017352 0.88 BTK (0.42) KDM4ENPC1TGFBR1SMN1; SMN2NPSR1
SCHEMBL10017011 0.86 MAPK9 (0.40) KDM4ENPC1SMN1; SMN2NPSR1MAPT
SCHEMBL10017233 0.86 DHODH (0.41) KDM4ENPC1TGFBR1SMN1; SMN2NPSR1
SCHEMBL10017162 0.86 MCL1 (0.40) KDM4ENPC1TGFBR1SMN1; SMN2NPSR1
SCHEMBL10017012 0.84 PTGS1 (0.40) KDM4ENPC1TGFBR1SMN1; SMN2NPSR1
SCHEMBL10017003 0.83 ADORA3 (0.40) KDM4ENPC1TGFBR1SMN1; SMN2NPSR1
SCHEMBL10016883 0.82 ABL1 (0.36) KDM4ENPC1TGFBR1SMN1; SMN2NPSR1
SCHEMBL10017349 0.82 BTK (0.41) KDM4ENPC1TGFBR1SMN1; SMN2NPSR1
SCHEMBL10032471 0.79 GRM5 (0.44) KDM4ENPC1TGFBR1SMN1; SMN2NPSR1
SCHEMBL10032672 0.77 DHODH (0.41) KDM4ENPC1TGFBR1SMN1; SMN2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012005214-A1 ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME JNC株式会社 (JP) 2012-01-12 WO disclosed