SCHEMBL10017352

SCHEMBL10017352

Cc1ccc2cc(-c3c4ccccc4c(-c4ccc(-c5ccccn5)c5ccccc45)c4ccccc34)ccc2c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BTK Q06187 1/20 0.42
PKM P14618 4/20 0.40
TP53 P04637 3/20 0.40
KDM4E B2RXH2 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
NPC1 O15118 3/20 0.40
ALDH1A1 P00352 2/20 0.40
HSD17B10 Q99714 2/20 0.40
RAB9A P51151 2/20 0.40
HPGD P15428 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
MAPT P10636 3/20 0.39
LMNA P02545 2/20 0.39
NPSR1 Q6W5P4 2/20 0.39
TSHR P16473 1/20 0.39
KLF5 Q13887 1/20 0.39
METAP2 P50579 1/20 0.39
METAP1 P53582 1/20 0.39
CBFB Q13951 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10017349 0.93 BTK (0.41) BTKPKMTP53KDM4ESMN1; SMN2
SCHEMBL10017233 0.92 DHODH (0.41) BTKPKMTP53KDM4ESMN1; SMN2
SCHEMBL10017003 0.89 ADORA3 (0.40) BTKPKMTP53KDM4ESMN1; SMN2
SCHEMBL10016883 0.89 ABL1 (0.36) BTKPKMTP53KDM4ESMN1; SMN2
SCHEMBL10017002 0.88 KDM4E (0.38) PKMTP53KDM4ESMN1; SMN2NPC1
SCHEMBL10032471 0.85 GRM5 (0.44) PKMTP53KDM4ESMN1; SMN2NPC1
SCHEMBL10017007 0.84 MAPT (0.41) KDM4ENPC1ALDH1A1RAB9AMEN1
SCHEMBL10017104 0.84 CYP1A2 (0.42) BTKPKMTP53KDM4ESMN1; SMN2
SCHEMBL10017014 0.84 PSMB5 (0.37) KDM4ENPC1ALDH1A1HSD17B10RAB9A
SCHEMBL10017019 0.83 MEN1 (0.41) TP53KDM4ENPC1ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012005214-A1 ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME JNC株式会社 (JP) 2012-01-12 WO disclosed