Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 12/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 12/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 7/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10017353 | 0.95 | CYP11B1 (0.49) | CYP11B2CYP11B1CYP17A1CYP19A1NPC1 | |
| SCHEMBL10017226 | 0.93 | CYP11B2 (0.51) | CYP11B2CYP11B1CYP17A1CYP19A1NPC1 | |
| SCHEMBL10032675 | 0.87 | CYP11B2 (0.55) | CYP11B2CYP11B1CYP17A1CYP19A1NPC1 | |
| SCHEMBL10032639 | 0.87 | CYP11B2 (0.55) | CYP11B2CYP11B1CYP17A1CYP19A1NPC1 | |
| SCHEMBL10017201 | 0.87 | MAPT (0.46) | NPC1MAPTRAB9ADHODHLMNA | |
| SCHEMBL10016887 | 0.87 | CYP11B1 (0.44) | CYP11B2CYP11B1CYP17A1CYP19A1NPC1 | |
| SCHEMBL10017350 | 0.86 | MAPT (0.47) | NPC1MAPTRAB9ALMNA | |
| SCHEMBL25759296 | 0.86 | CYP11B1 (0.56) | CYP11B2CYP11B1CYP17A1CYP19A1NPC1 | |
| SCHEMBL10016782 | 0.85 | MAPT (0.48) | CYP11B2CYP11B1CYP17A1CYP19A1MAPT | |
| SCHEMBL10016744 | 0.84 | CYP11B1 (0.62) | CYP11B2CYP11B1CYP17A1CYP19A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012005214-A1 | ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME | JNC株式会社 (JP) | 2012-01-12 | — | — | WO | disclosed |