SCHEMBL10016744

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17320747	0.96	CYP11B1 (0.60)	CYP11B1CYP11B2CYP17A1CYP19A1NPC1
	SCHEMBL13146179	0.90	CYP11B1 (0.72)	CYP11B1CYP11B2CYP17A1CYP19A1NPC1
	SCHEMBL10017353	0.89	CYP11B1 (0.49)	CYP11B1CYP11B2CYP17A1CYP19A1NPC1
	SCHEMBL10032221	0.87	CYP11B2 (0.73)	CYP11B1CYP11B2CYP17A1CYP19A1NPC1
	SCHEMBL17320746	0.87	CYP11B1 (0.56)	CYP11B1CYP11B2CYP17A1CYP19A1NPC1
	SCHEMBL17320744	0.87	CYP11B2 (0.64)	CYP11B1CYP11B2CYP17A1CYP19A1NPC1
	SCHEMBL17320736	0.87	CYP11B1 (0.64)	CYP11B1CYP11B2CYP17A1CYP19A1NPC1
	SCHEMBL18165286	0.86	CYP11B1 (0.63)	CYP11B1CYP11B2CYP17A1CYP19A1NPC1
	SCHEMBL1102718	0.86	TNF (0.50)	CYP11B1CYP11B2CYP17A1CYP19A1NPC1
	SCHEMBL13827884	0.86	CYP11B1 (0.59)	CYP11B1CYP11B2CYP17A1CYP19A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.