SCHEMBL10017552

SCHEMBL10017552

CCC1CCC(C2CCC(OC(=O)c3cc(N)cc(N)c3)CC2)CC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SERPINE1 P05121 2/20 0.45
CYP19A1 P11511 1/20 0.42
NPC1 O15118 2/20 0.38
CYP1A2 P05177 2/20 0.38
CYP2D6 P10635 2/20 0.38
HTR3E A5X5Y0 2/20 0.38
HTR3B O95264 2/20 0.38
HTR3A P46098 2/20 0.38
HTR3D Q70Z44 2/20 0.38
HTR3C Q8WXA8 2/20 0.38
MEN1 O00255 1/20 0.38
CYP2C19 P33261 1/20 0.38
KMT2A Q03164 1/20 0.38
NR1I2 O75469 1/20 0.38
POLB P06746 1/20 0.38
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
PTGER4 P35408 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1688862 0.87 CYP1A2 (0.51) SERPINE1CYP19A1NPC1CYP1A2CYP2D6
SCHEMBL13909981 0.86 SERPINE1 (0.43) SERPINE1NPC1CYP1A2CYP2D6HTR3E
SCHEMBL10054733 0.86 SERPINE1 (0.40) SERPINE1NPC1CYP1A2CYP2D6HTR3E
SCHEMBL17123440 0.85 SERPINE1 (0.40) SERPINE1NPC1CYP1A2CYP2D6HTR3E
SCHEMBL16265110 0.85 SERPINE1 (0.40) SERPINE1NPC1CYP1A2CYP2D6HTR3E
SCHEMBL12314556 0.84 SERPINE1 (0.46) SERPINE1NPC1CYP1A2CYP2D6HTR3E
SCHEMBL105316 0.84 SERPINE1 (0.49) SERPINE1CYP19A1NPC1CYP1A2CYP2D6
SCHEMBL17720302 0.84 SERPINE1 (0.49) SERPINE1CYP19A1NPC1CYP1A2CYP2D6
SCHEMBL11996902 0.82 SERPINE1 (0.50) SERPINE1NPC1CYP1A2CYP2D6HTR3E
SCHEMBL14300472 0.82 SERPINE1 (0.48) SERPINE1CYP19A1NPC1CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9541795-B2 Liquid crystal display device and method for manufacturing the same SONY CORPORATION (JP) 2017-01-10 US disclosed
US-9523889-B2 Liquid crystal display unit and method of manufacturing the same SONY CORPORATION (JP) 2016-12-20 US disclosed
US-9507210-B2 Liquid crystal display and method of manufacturing the same SONY CORPORATION (JP) 2016-11-29 US disclosed
US-9470929-B2 Liquid crystal display unit and method of manufacturing the same SONY CORPORATION (JP) 2016-10-18 US disclosed
US-9465244-B2 Liquid crystal display SONY CORPORATION (JP) 2016-10-11 US disclosed
US-9366910-B2 Liquid crystal display and method of manufacturing the same SONY CORPORATION (JP) 2016-06-14 US disclosed
US-20160011463-A1 LIQUID CRYSTAL DISPLAY UNIT AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2016-01-14 US disclosed
US-9235084-B2 Liquid crystal display device and manufacturing method thereof SONY CORPORATION (JP) 2016-01-12 US disclosed
US-9146425-B2 Liquid crystal display and method of manufacturing the same SONY CORPORATION (JP) 2015-09-29 US disclosed
US-20150146148-A1 LIQUID CRYSTAL DISPLAY UNIT AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2015-05-28 US disclosed
US-20120212697-A1 LIQUID CRYSTAL DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF SONY CORPORATION (JP) 2012-08-23 US disclosed
US-20120212691-A1 LIQUID CRYSTAL DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF SONY CORPORATION (JP) 2012-08-23 US disclosed
US-20120026440-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING THE SAME SONY CORPORATION (JP) 2012-02-02 US disclosed
US-20110273652-A1 LIQUID CRYSTAL DISPLAY AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2011-11-10 US disclosed
US-20110257361-A1 ALKYL BENZENE TETRACARBOXYLIC DIANHYDRIDE, MANUFACTURING METHOD THEREOF, POLYIMIDE, AND APPLICATION THEREOF NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2011-10-20 US disclosed
US-20110157531-A1 LIQUID CRYSTAL DISPLAY UNIT AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2011-06-30 US disclosed
US-20110134382-A1 LIQUID CRYSTAL DISPLAY ELEMENT AND LIQUID CRYSTAL DISPLAY DEVICE SONY CORPORATION (JP) 2011-06-09 US disclosed
WO-2010071167-A1 ALKYL BENZENE TETRACARBOXYLIC DIANHYDRIDE, MANUFACTURING METHOD THEREOF, POLYIMIDE, AND APPLICATION THEREOF 日産化学工業株式会社 (JP) 2010-06-24 WO disclosed
WO-2010047316-A1 LIQUID CRYSTAL ALIGNING AGENT AND LIQUID CRYSTAL ELEMENT USING SAME 日産化学工業株式会社 (JP) 2010-04-29 WO disclosed
WO-2009154208-A1 LIQUID-CRYSTAL ALIGNMENT MATERIAL, LIQUID-CRYSTAL DISPLAY ELEMENT EMPLOYING SAME, AND NOVEL DIAMINE 日産化学工業株式会社 (JP) 2009-12-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160011463-A1 LIQUID CRYSTAL DISPLAY UNIT AND METHOD OF MANUFACTURING THE SAME PYM1, PDCD2L, SDAD1 SERPINE1 1800/4885CYP19A1 2657/4885NPC1 4025/4885
US-20110257361-A1 ALKYL BENZENE TETRACARBOXYLIC DIANHYDRIDE, MANUFACTURING METHOD THEREOF, POLYIMIDE, AND APPLICATION THEREOF PBRM1, PUF60, ALKBH1 SERPINE1 3574/4885CYP19A1 3286/4885NPC1 4754/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.