Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11541914 | 0.87 | HSD17B10 (0.46) | HSD17B10CXCR5MEN1KMT2AALDH1A1 | |
| SCHEMBL5881855 | 0.86 | ORAI1 (0.49) | HSD17B10CXCR5MEN1KMT2AALDH1A1 | |
| SCHEMBL10017630 | 0.82 | GAA (0.35) | HSD17B10CXCR5MEN1KMT2AALDH1A1 | |
| SCHEMBL4432897 | 0.79 | HSD17B10 (0.41) | HSD17B10CXCR5MEN1KMT2AALDH1A1 | |
| SCHEMBL13928781 | 0.72 | HSD17B10 (0.40) | HSD17B10CXCR5MEN1KMT2AALDH1A1 | |
| SCHEMBL10642511 | 0.72 | HSD17B10 (0.44) | HSD17B10MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL31006518 | 0.70 | HSD17B10 (0.57) | HSD17B10CXCR5MEN1KMT2AALDH1A1 | |
| SCHEMBL24644599 | 0.70 | GAA (0.33) | HSD17B10MEN1KMT2AALDH1A1GAA | |
| SCHEMBL16533511 | 0.69 | HSD17B10 (0.35) | HSD17B10MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5917949 | 0.69 | HSD17B10 (0.35) | HSD17B10MEN1KMT2AGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2886549-A1 | Ruthenium complex ligand, ruthenium complex and the use of the complex as a catalyst in olefin metathesis reactions | Zannan Scitech Co., Ltd. (CN) | 2015-06-24 | — | — | EP | disclosed |
| EP-1905777-B1 | RUTHENIUM COMPLEX LIGAND, RUTHENIUM COMPLEX, CARRIED RUTHENIUM COMPLEX CATALYST AND THE PREPARING METHODS AND THE USE THEREOF | ZANNAN SCITECH CO LTD (CN) | 2015-05-06 | — | — | EP | disclosed |
| US-8288576-B2 | Recyclable ruthenium catalysts for metathesis reactions | ZANNAN SCITECH CO., LTD. (CN) | 2012-10-16 | — | — | US | disclosed |
| US-8288576-B2 | Recyclable ruthenium catalysts for metathesis reactions | ZANNAN SCITECH CO., LTD. (CN) | 2012-10-16 | — | — | US | disclosed |
| US-20120016093-A1 | RECYCLABLE RUTHENIUM CATALYSTS FOR METATHESIS REACTIONS | ZANNAN SCITECH CO., LTD. (CN) | 2012-01-19 | — | — | US | disclosed |
| US-20120016093-A1 | RECYCLABLE RUTHENIUM CATALYSTS FOR METATHESIS REACTIONS | ZANNAN SCITECH CO., LTD. (CN) | 2012-01-19 | — | — | US | disclosed |
| US-8049025-B2 | Recyclable ruthenium catalysts for metathesis reactions | ZANNAN SCITECH CO., LTD. (CN) | 2011-11-01 | — | — | US | disclosed |
| US-8049025-B2 | Recyclable ruthenium catalysts for metathesis reactions | ZANNAN SCITECH CO., LTD. (CN) | 2011-11-01 | — | — | US | disclosed |
| US-20100041844-A1 | RECYCLABLE RUTHENIUM CATALYSTS FOR METATHESIS REACTIONS | ZHENG-YUN JAMES ZHAN (CN) | 2010-02-18 | — | — | US | disclosed |
| US-20100041844-A1 | RECYCLABLE RUTHENIUM CATALYSTS FOR METATHESIS REACTIONS | ZHENG-YUN JAMES ZHAN (CN) | 2010-02-18 | — | — | US | disclosed |
| US-7632772-B2 | Recyclable ruthenium catalysts for metathesis reactions | Zhan, Zheng-Yun James (CN) | 2009-12-15 | — | — | US | disclosed |
| US-7632772-B2 | Recyclable ruthenium catalysts for metathesis reactions | Zhan, Zheng-Yun James (CN) | 2009-12-15 | — | — | US | disclosed |
| EP-1905777-A1 | RUTHENIUM COMPLEX LIGAND, RUTHENIUM COMPLEX, CARRIED RUTHENIUM COMPLEX CATALYST AND THE PREPARING METHODS AND THE USE THEREOF | Zhan, Zheng-Yun (CN) | 2008-04-02 | — | — | EP | disclosed |
| US-20070043180-A1 | Recyclable ruthenium catalysts for metathesis reactions | ZHENG-YUN JAMES ZHAN (CN) | 2007-02-22 | — | — | US | disclosed |
| US-20070043180-A1 | Recyclable ruthenium catalysts for metathesis reactions | ZHENG-YUN JAMES ZHAN (CN) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016093-A1 | RECYCLABLE RUTHENIUM CATALYSTS FOR METATHESIS REACTIONS | RPIA, REV1, RCSD1 | HSD17B10 2790/4885CXCR5 1077/4885MEN1 4261/4885 |
| US-20100041844-A1 | RECYCLABLE RUTHENIUM CATALYSTS FOR METATHESIS REACTIONS | RPIA, REV1, RCSD1 | HSD17B10 2790/4885CXCR5 1077/4885MEN1 4261/4885 |
| US-20070043180-A1 | Recyclable ruthenium catalysts for metathesis reactions | RPIA, REV1, RCSD1 | HSD17B10 2790/4885CXCR5 1077/4885MEN1 4261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.