Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11541914 | 0.87 | HSD17B10 (0.46) | HSD17B10CXCR5ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL12670376 | 0.86 | PTGDR (0.41) | PTGDRPTGDR2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL4427150 | 0.86 | PTGDR (0.41) | PTGDRPTGDR2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL12670381 | 0.84 | CYP1A2 (0.50) | PTGDRPTGDR2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL12670365 | 0.83 | PTGDR (0.39) | PTGDRPTGDR2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL12670380 | 0.83 | MAPT (0.44) | PTGDRPTGDR2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL12670371 | 0.81 | PTGDR (0.41) | PTGDRPTGDR2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL12670369 | 0.81 | POLB (0.41) | PTGDRPTGDR2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL12670374 | 0.81 | MAPT (0.52) | PTGDRPTGDR2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL12670383 | 0.81 | POLB (0.41) | PTGDRPTGDR2ALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825167-B2 | Dental composition containing unsaturated halogenated aryl alkyl ether components | 3M ESPE AG (DE) | 2010-11-02 | — | — | US | disclosed |
| US-7825167-B2 | Dental composition containing unsaturated halogenated aryl alkyl ether components | 3M ESPE AG (DE) | 2010-11-02 | — | — | US | disclosed |
| EP-1765262-B1 | DENTAL COMPOSITION CONTAINING UNSATURATED HALOGENATED ARYL ALKYL ETHER COMPONENTS | 3M ESPE AG (DE) | 2009-03-04 | — | — | EP | disclosed |
| EP-1765262-B1 | DENTAL COMPOSITION CONTAINING UNSATURATED HALOGENATED ARYL ALKYL ETHER COMPONENTS | 3M ESPE AG (DE) | 2009-03-04 | — | — | EP | disclosed |
| US-20080051488-A1 | Dental Composition Containing Unsaturated Halogenated Aryl Alkyl Ether Components | 3M DEUTSCHLAND GMBH (DE) | 2008-02-28 | — | — | US | disclosed |
| US-20080051488-A1 | Dental Composition Containing Unsaturated Halogenated Aryl Alkyl Ether Components | 3M DEUTSCHLAND GMBH (DE) | 2008-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051488-A1 | Dental Composition Containing Unsaturated Halogenated Aryl Alkyl Ether Components | DDX3X, TAS2R39, TAS1R1 | HSD17B10 2563/4885PTGDR 134/4885PTGDR2 269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.