Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.31 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1702497 | 0.83 | TSHR (0.38) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4637933 | 0.81 | TSHR (0.41) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8524798 | 0.80 | TSHR (0.35) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL18107148 | 0.79 | ALDH1A1 (0.37) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| Ammonia Solution, Strong SCHEMBL8523447 | 0.79 | TSHR (0.34) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL21439808 | 0.76 | TSHR (0.46) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8374242 | 0.76 | ALDH1A1 (0.33) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL28537993 | 0.75 | ALDH1A1 (0.35) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| Sulfuric Acid SCHEMBL2213085 | 0.74 | ALDH1A1 (0.41) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL174734 | 0.74 | TSHR (0.48) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2814575-B1 | CONDITIONING COMPOSITION ADDITIVE FOR PROVIDING IMMEDIATE AND LONG LASTING BENEFITS TO KERATIN SUBSTRATES | HERCULES LLC (US) | 2018-04-11 | — | — | EP | disclosed |
| US-RE42127-E1 | applying to the hair or skin a treatment solution containing a copolymer of monomers of (meth)acrylamidopropyl trimethylammonium chloride, (meth)acrylic acid, 2-(meth)acrylamido-2-methylpropane sulfonic acid and methyl acrylate; shampoo, bar soap, sunscreen agent, shaving cream | NALCO COMPANY (US) | 2011-02-08 | — | — | US | disclosed |
| US-RE42025-E1 | Ampholyte polymers for use in personal care products | NALCO COMPANY (US) | 2011-01-11 | — | — | US | disclosed |
| EP-1021471-B1 | AMPHOLYTE POLYMERS FOR USE IN PERSONAL CARE PRODUCTS | CALGON CORP (US) | 2007-08-29 | — | — | EP | disclosed |
| CN-1285852-A | Ampholyte polymers for use in personal care products | CALGON CORP (US) | 2001-02-28 | — | — | CN | disclosed |
| US-6066315-A | HAIR CONDITIONING POLYMERS CONTAINING (METH)ACRYLAMIDOPROPYLTRIMETHYL AMMONIUM CHLORIDE, METH(ACRYLIC ACID) AND A C1-22 ALKYL (METH)ACRYLATE | CALGON CORPORATION (US) | 2000-05-23 | — | — | US | disclosed |
| US-5879670-A | TREATMENT OF A KERATIN-CONTAINING SUBSTRATE | CALGON CORPORATION (US) | 1999-03-09 | — | — | US | disclosed |