Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.47 |
| ▸ | PRKDC | P78527 | 3/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10049683 | 0.84 | PDK2 (0.43) | PDK2PRKDCPIK3CAPIK3CDPIK3CB | |
| SCHEMBL24605103 | 0.83 | PDK2 (0.43) | PDK2PRKDCPIK3CAPIK3CDPIK3CB | |
| SCHEMBL1711032 | 0.81 | PDK2 (0.47) | PDK2PRKDCPIK3CAPIK3CDPIK3CB | |
| SCHEMBL15449609 | 0.78 | PDK2 (0.40) | PDK2PRKDCPIK3CAHSD17B1HSD17B2 | |
| SCHEMBL1710808 | 0.76 | ALK (0.42) | PDK2PRKDCPIK3CAMAPTKMT2A | |
| SCHEMBL10262943 | 0.76 | PDK2 (0.39) | PDK2PRKDCPIK3CAPIK3CDPIK3CB | |
| SCHEMBL13868673 | 0.76 | HSD17B1 (0.40) | PDK2PRKDCPIK3CAPIK3CDPIK3CB | |
| SCHEMBL15452246 | 0.75 | PDK2 (0.38) | PDK2PRKDCPIK3CAPIK3CDPIK3CB | |
| SCHEMBL10262978 | 0.74 | PDK2 (0.37) | PDK2PIK3CAHSD17B1HSD17B2MAPT | |
| SCHEMBL10267942 | 0.74 | PDK2 (0.37) | PDK2HSD17B1HSD17B2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8123987-B2 | Chromene compounds | TOKUYAMA CORPORATION (JP) | 2012-02-28 | — | — | US | disclosed |
| US-20100230648-A1 | Chromene Compounds | TOKUYAMA CORPORATION (JP) | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100230648-A1 | Chromene Compounds | H1-4, RB1, H1-0 | PDK2 1595/4885PRKDC 3262/4885PIK3CA 663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.