Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10018205 | 0.97 | MEN1 (0.39) | MEN1GAAKMT2APDK2HSP90AA1 | |
| SCHEMBL10018176 | 0.88 | MEN1 (0.44) | MEN1GAAKMT2APDK2HSP90AA1 | |
| SCHEMBL25954035 | 0.86 | MEN1 (0.41) | MEN1GAAKMT2APDK2HSP90AA1 | |
| SCHEMBL24404034 | 0.86 | MEN1 (0.41) | MEN1GAAKMT2APDK2HSP90AA1 | |
| SCHEMBL25954104 | 0.82 | MEN1 (0.39) | MEN1GAAKMT2APDK2HSP90AA1 | |
| SCHEMBL8513625 | 0.82 | MEN1 (0.43) | MEN1GAAKMT2APDK2HSP90AA1 | |
| SCHEMBL10018183 | 0.81 | GAA (0.43) | MEN1GAAKMT2APDK2HSP90AA1 | |
| SCHEMBL10049970 | 0.80 | MEN1 (0.37) | MEN1GAAKMT2APDK2 | |
| SCHEMBL25954584 | 0.79 | MEN1 (0.38) | MEN1GAAKMT2APDK2PDE7A | |
| SCHEMBL16360204 | 0.78 | MEN1 (0.38) | MEN1GAAKMT2APDK2HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8123987-B2 | Chromene compounds | TOKUYAMA CORPORATION (JP) | 2012-02-28 | — | — | US | disclosed |
| US-20100230648-A1 | Chromene Compounds | TOKUYAMA CORPORATION (JP) | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100230648-A1 | Chromene Compounds | H1-4, RB1, H1-0 | MEN1 1057/4885GAA 4225/4885KMT2A 269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.