SCHEMBL10018352

SCHEMBL10018352

CO[C@@H](C(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.68
CYP3A4 P08684 1/20 0.68
KMT2A Q03164 4/20 0.59
POLB P06746 2/20 0.59
MAPT P10636 2/20 0.59
NPC1 O15118 2/20 0.59
RAB9A P51151 2/20 0.59
MEN1 O00255 2/20 0.59
L3MBTL1 Q9Y468 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
CES2 O00748 1/20 0.53
LMNA P02545 1/20 0.53
CES1 P23141 1/20 0.53
GAA P10253 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.51
NPSR1 Q6W5P4 1/20 0.51
HTT P42858 1/20 0.49
TSHR P16473 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26160 1.00 ALDH1A1 (0.68) ALDH1A1CYP3A4KMT2APOLBMAPT
Methoxymethane SCHEMBL28231191 0.98 ALDH1A1 (0.66) ALDH1A1CYP3A4KMT2APOLBMAPT
Water SCHEMBL23466907 0.98 ALDH1A1 (0.66) ALDH1A1CYP3A4KMT2APOLBMAPT
Benzil SCHEMBL11335913 0.94 ALDH1A1 (0.62) ALDH1A1CYP3A4KMT2APOLBMAPT
Benzophenone SCHEMBL28254452 0.94 ALDH1A1 (0.62) ALDH1A1CYP3A4KMT2APOLBMAPT
Propane SCHEMBL28182556 0.94 ALDH1A1 (0.62) ALDH1A1CYP3A4KMT2APOLBMAPT
Acetophenone SCHEMBL27945960 0.93 ALDH1A1 (0.65) ALDH1A1CYP3A4KMT2APOLBMAPT
Benzoin SCHEMBL28077515 0.91 LMNA (0.70) ALDH1A1CYP3A4KMT2APOLBMAPT
Benzoquinone SCHEMBL28110115 0.91 ALDH1A1 (0.58) ALDH1A1CYP3A4KMT2APOLBMAPT
Anisole SCHEMBL28145106 0.91 MAPT (0.68) ALDH1A1CYP3A4KMT2APOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2418536-B1 LIQUID CRYSTAL DISPLAY DEVICE and COMPOSITION FOR FORMING a POLYMER LAYER SHARP KK (JP) 2014-09-17 EP disclosed
EP-2418536-A1 LIQUID CRYSTAL DISPLAY DEVICE, METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE, COMPOSITION FOR FORMING POLYMER LAYER, AND COMPOSITION FOR FORMING LIQUID CRYSTAL LAYER Sharp Kabushiki Kaisha (JP) 2012-02-15 EP disclosed