Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10018488 | 0.94 | CYP19A1 (0.33) | MAOAMAOBACHECYP2D6L3MBTL1 | |
| SCHEMBL10018484 | 0.83 | RXFP1 (0.37) | MAOAMAOBACHECYP2D6TOP2A | |
| SCHEMBL12383089 | 0.82 | RXFP1 (0.47) | MAOAMAOBACHECYP2D6HDAC3 | |
| SCHEMBL4570444 | 0.80 | MAOA (0.46) | MAOAMAOBACHECYP2D6TOP2A | |
| SCHEMBL20717612 | 0.80 | MAOA (0.46) | MAOAMAOBACHECYP2D6TOP2A | |
| SCHEMBL10100904 | 0.80 | MAOA (0.46) | MAOAMAOBACHECYP2D6TOP2A | |
| SCHEMBL17570273 | 0.80 | CYP19A1 (0.32) | MAOAMAOBACHE | |
| SCHEMBL6113990 | 0.78 | MAOA (0.43) | MAOAMAOBACHECYP2D6TOP2A | |
| SCHEMBL10100902 | 0.78 | MAOA (0.43) | MAOAMAOBACHECYP2D6TOP2A | |
| SCHEMBL261829 | 0.77 | MAOA (0.43) | MAOAMAOBACHECYP2D6TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101699-B2 | Electron-transporting polymers | GENERAL ELECTRIC COMPANY (US) | 2012-01-24 | — | — | US | disclosed |
| US-20100137538-A1 | ELECTRON-TRANSPORTING POLYMERS | GENERAL ELECTRIC COMPANY (US) | 2010-06-03 | — | — | US | disclosed |