Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 4/20 | 0.37 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10018489 | 0.95 | ADH5 (0.34) | RXFP1MCL1GSK3BCDK4CDK2 | |
| SCHEMBL14424740 | 0.87 | MAOA (0.42) | MAOAMAOBACHECYP2D6TOP2A | |
| SCHEMBL12383089 | 0.86 | RXFP1 (0.47) | RXFP1MAOAMAOBACHECYP2D6 | |
| SCHEMBL10018482 | 0.85 | HTT (0.35) | MCL1HTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL261829 | 0.83 | MAOA (0.43) | MAOAMAOBACHECYP2D6HTT | |
| SCHEMBL261485 | 0.83 | MAOA (0.43) | MAOAMAOBACHECYP2D6HTT | |
| SCHEMBL261774 | 0.83 | MAOA (0.43) | MAOAMAOBACHECYP2D6HTT | |
| SCHEMBL10018486 | 0.83 | MAOA (0.41) | RXFP1MAOAMAOBACHECYP2D6 | |
| SCHEMBL20717612 | 0.82 | MAOA (0.46) | MAOAMAOBACHECYP2D6HDAC3 | |
| SCHEMBL10100904 | 0.82 | MAOA (0.46) | MAOAMAOBACHECYP2D6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101699-B2 | Electron-transporting polymers | GENERAL ELECTRIC COMPANY (US) | 2012-01-24 | — | — | US | disclosed |
| US-20100137538-A1 | ELECTRON-TRANSPORTING POLYMERS | GENERAL ELECTRIC COMPANY (US) | 2010-06-03 | — | — | US | disclosed |