Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 11/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GALK1 | P51570 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17057190 | 0.94 | ALOX5 (0.40) | ALOX5PDK2LIMK1MEN1APAF1 | |
| SCHEMBL17057191 | 0.94 | PDK2 (0.42) | ALOX5PDK2LIMK1PGR | |
| SCHEMBL17640463 | 0.91 | MEN1 (0.34) | ALOX5PDK2LIMK1MEN1LMNA | |
| SCHEMBL10018862 | 0.89 | ALOX5 (0.44) | ALOX5PDK2LIMK1TDO2PGR | |
| SCHEMBL10018859 | 0.89 | ALOX5 (0.44) | ALOX5PDK2LIMK1TDO2PGR | |
| SCHEMBL17640347 | 0.87 | PDK2 (0.37) | ALOX5PDK2LIMK1MEN1LMNA | |
| SCHEMBL17640307 | 0.86 | PDK2 (0.36) | ALOX5PDK2LIMK1MEN1LMNA | |
| SCHEMBL17425707 | 0.86 | PDK2 (0.36) | ALOX5PDK2LIMK1MEN1LMNA | |
| SCHEMBL17640468 | 0.86 | PDK2 (0.36) | ALOX5PDK2LIMK1MEN1LMNA | |
| SCHEMBL21433053 | 0.85 | ALOX5 (0.36) | ALOX5PDK2LIMK1RARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8743031-B2 | Dibenzothiophene compound and organic light-emitting element based on the same | CANON KABUSHIKI KAISHA (JP) | 2014-06-03 | — | — | US | disclosed |
| US-8743031-B2 | Dibenzothiophene compound and organic light-emitting element based on the same | CANON KABUSHIKI KAISHA (JP) | 2014-06-03 | — | — | US | disclosed |
| US-20120075171-A1 | DIBENZOTHIOPHENE COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT BASED ON THE SAME | CANON KABUSHIKI KAISHA (JP) | 2012-03-29 | — | — | US | disclosed |
| US-20120075171-A1 | DIBENZOTHIOPHENE COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT BASED ON THE SAME | CANON KABUSHIKI KAISHA (JP) | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120075171-A1 | DIBENZOTHIOPHENE COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT BASED ON THE SAME | TPT1, RFT1, ARNT | ALOX5 2608/4885PDK2 2335/4885LIMK1 2383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.