SCHEMBL10019610

SCHEMBL10019610

CCCC1CCC(COc2ccc(-c3ccc(OCC)c(F)c3C=O)c(C=O)c2F)CC1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 5/20 0.34
PTGDR2 Q9Y5Y4 4/20 0.34
POLB P06746 1/20 0.34
LMNA P02545 1/20 0.33
RIPK1 Q13546 1/20 0.33
SLC6A9 P48067 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
HTR2A P28223 2/20 0.32
HTR2C P28335 2/20 0.32
HTR2B P41595 2/20 0.32
GAA P10253 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
HPGD P15428 1/20 0.31
PDE4A P27815 1/20 0.31
PDE4B Q07343 1/20 0.31
PDE4C Q08493 1/20 0.31
PDE4D Q08499 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1311479 0.86 RIPK1 (0.38) BRD4PTGDR2RIPK1HTR2AHTR2C
SCHEMBL12366402 0.86 RIPK1 (0.42) BRD4RIPK1SLC6A9HTR2AHTR2C
SCHEMBL28700888 0.86 RIPK1 (0.42) BRD4RIPK1SLC6A9HTR2AHTR2C
SCHEMBL15445797 0.86 RIPK1 (0.42) BRD4RIPK1SLC6A9HTR2AHTR2C
SCHEMBL10019609 0.85 ERN1 (0.37) BRD4POLBLMNARIPK1SLC6A9
SCHEMBL10019612 0.83 BRD4 (0.38) BRD4PTGDR2RIPK1SLC6A9HPGD
SCHEMBL17527882 0.83 RIPK1 (0.36) POLBLMNARIPK1ALDH1A1MAPT
SCHEMBL8448300 0.82 RIPK1 (0.39) BRD4RIPK1SLC6A9ALDH1A1MAPT
SCHEMBL15445815 0.82 RIPK1 (0.39) BRD4RIPK1SLC6A9ALDH1A1MAPT
SCHEMBL8448296 0.82 RIPK1 (0.39) BRD4RIPK1SLC6A9ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2669263-B1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2017-11-22 EP disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
EP-2669263-A1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY JNC Corporation (JP) 2013-12-04 EP disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
WO-2012086437-A1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY JNC株式会社 (JP) 2012-06-28 WO disclosed