SCHEMBL10019672

SCHEMBL10019672

CCOc1ccc(OC(=O)c2ccc3c(c2F)C(F)(F)C(F)(F)c2c-3ccc(OCC)c2F)c(F)c1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.41
FFAR1 O14842 7/20 0.39
PPARD Q03181 4/20 0.39
CPS1 P31327 2/20 0.35
MAOB P27338 2/20 0.35
PTGS2 P35354 1/20 0.35
FFAR4 Q5NUL3 1/20 0.34
FAAH O00519 1/20 0.34
LMNA P02545 1/20 0.34
TP53 P04637 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MAPT P10636 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MAOA P21397 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10019670 0.93 ESR1 (0.39) KDM4EFFAR1PPARDPTGS2MAPT
SCHEMBL10019871 0.93 KDM4E (0.41) KDM4EFFAR1PPARDCPS1MAOB
SCHEMBL10019358 0.89 KDM4E (0.39) KDM4ELMNATP53MAPT
SCHEMBL10019356 0.89 ALDH1A1 (0.34) KDM4EPTGS2SMN1; SMN2
SCHEMBL10019668 0.88 PDE5A (0.35) PTGS2FAAHSMN1; SMN2MAPT
SCHEMBL15257942 0.86 ALDH1A1 (0.34) KDM4EPTGS2LMNASMN1; SMN2
SCHEMBL10019667 0.86 ESR1 (0.36) KDM4EFFAR1PPARDPTGS2LMNA
SCHEMBL10019361 0.84 MAPT (0.44) KDM4EPTGS2FFAR4SMN1; SMN2MAPT
SCHEMBL19622078 0.84 ESR1 (0.37) KDM4EFFAR1PPARDMAOBPTGS2
SCHEMBL10019636 0.83 ALDH1A1 (0.31) FFAR1PPARDPTGS2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2669263-B1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2017-11-22 EP disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
WO-2012086437-A1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY JNC株式会社 (JP) 2012-06-28 WO disclosed