SCHEMBL10019947

SCHEMBL10019947

C=CCCC1CCC(COc2ccc3c(c2F)C(F)C(F)c2c-3ccc(OCC)c2F)CC1

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.34
HTR2A P28223 4/20 0.32
HTR2C P28335 4/20 0.32
HTR2B P41595 2/20 0.32
PTGDR2 Q9Y5Y4 2/20 0.31
HPGD P15428 1/20 0.30
NR3C1 P04150 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13417736 0.89 RIPK1 (0.38) RIPK1HTR2AHTR2CHTR2BHPGD
SCHEMBL10019913 0.89
SCHEMBL10019949 0.89 RIPK1 (0.33) RIPK1
SCHEMBL10019934 0.87 RIPK1 (0.37) RIPK1HTR2AHTR2CHTR2BPTGDR2
SCHEMBL10020162 0.86
SCHEMBL13417733 0.86 RIPK1 (0.35) RIPK1HTR2AHTR2CHTR2BHPGD
SCHEMBL10019805 0.86 NAAA (0.34)
SCHEMBL10019593 0.86
SCHEMBL10020059 0.85 HPGD (0.39) PTGDR2HPGD
SCHEMBL10019541 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2669263-B1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2017-11-22 EP disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
WO-2012086437-A1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY JNC株式会社 (JP) 2012-06-28 WO disclosed