SCHEMBL10019976

SCHEMBL10019976

CCCCCc1ccc(-c2ccc3c(c2F)C(F)C(F)c2c-3ccc(CCC)c2F)c(F)c1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
RARB P10826 3/20 0.39
GPR3 P46089 1/20 0.35
S1PR1 P21453 1/20 0.35
TLR8 Q9NR97 6/20 0.34
HTR2A P28223 1/20 0.34
RARA P10276 1/20 0.33
RARG P13631 1/20 0.33
HTR1A P08908 1/20 0.33
HTR1D P28221 1/20 0.33
HTR1B P28222 1/20 0.33
LPL P06858 4/20 0.33
LIPG Q9Y5X9 4/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10020039 0.91 S1PR1 (0.40) RARBGPR3S1PR1TLR8HTR2A
SCHEMBL10020036 0.88 S1PR1 (0.37) RARBGPR3S1PR1TLR8HTR2A
SCHEMBL10019843 0.86 ESR1 (0.38) RARBHTR2ALPLLIPG
SCHEMBL10020116 0.86 S1PR1 (0.35) RARBS1PR1
SCHEMBL10019972 0.85 RARB (0.43) RARBHTR2ARARARARG
SCHEMBL10019971 0.85 CTSL (0.32)
SCHEMBL10019561 0.84 CTSL (0.40) LIPG
SCHEMBL10020009 0.84 HTT (0.34) RARBS1PR1HTR1AHTR1DHTR1B
SCHEMBL10019870 0.84 TYR (0.39) RARBGPR3LIPG
SCHEMBL10020160 0.82 TYR (0.37) GPR3LIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2669263-B1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2017-11-22 EP disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
WO-2012086437-A1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY JNC株式会社 (JP) 2012-06-28 WO disclosed