SCHEMBL10020009

SCHEMBL10020009

CCCCCc1ccc(OCc2ccc3c(c2F)C(F)C(F)c2c-3ccc(CCC)c2F)c(F)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.34
MAPT P10636 2/20 0.34
MAPK1 P28482 2/20 0.34
S1PR1 P21453 2/20 0.34
APAF1 O14727 1/20 0.34
THRB P10828 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
S1PR2 O95136 1/20 0.33
S1PR3 Q99500 1/20 0.33
LPAR2 Q9HBW0 1/20 0.33
NPC1 O15118 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
RAD52 P43351 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CTSL P07711 1/20 0.33
CTSS P25774 1/20 0.33
CTSK P43235 1/20 0.33
RARB P10826 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10020116 0.93 S1PR1 (0.35) HTTMAPTMAPK1S1PR1APAF1
SCHEMBL10020014 0.87 CTSL (0.33) CTSLCTSSCTSK
SCHEMBL10020140 0.86 RXRG (0.36) HTTMAPTMAPK1S1PR1APAF1
SCHEMBL10020020 0.86 GABRA1 (0.36) MAPTMAPK1S1PR1THRBL3MBTL1
SCHEMBL10019943 0.86 SMPD1 (0.38) HTTMAPTMAPK1APAF1THRB
SCHEMBL10019632 0.85 CTSL (0.38) HTTMAPTMEN1KMT2ACTSL
SCHEMBL10020135 0.85 CTSL (0.38) HTTMAPTMEN1KMT2ACTSL
SCHEMBL19621962 0.85 CTSL (0.38) HTTMAPTMEN1KMT2ACTSL
SCHEMBL10020039 0.85 S1PR1 (0.40) HTTMAPTS1PR1MEN1KMT2A
SCHEMBL10020011 0.84 HRH3 (0.40) MAPTMAPK1S1PR1L3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2669263-B1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2017-11-22 EP disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
WO-2012086437-A1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY JNC株式会社 (JP) 2012-06-28 WO disclosed