SCHEMBL10020044

SCHEMBL10020044

CCOc1ccc(C(=O)Oc2ccc3c(c2F)C(F)C(F)c2c-3ccc(OCC)c2F)c(F)c1F

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.34
TDP1 Q9NUW8 2/20 0.34
LMNA P02545 1/20 0.34
GAA P10253 1/20 0.34
POLB P06746 1/20 0.34
ALDH1A1 P00352 3/20 0.33
KDM4E B2RXH2 2/20 0.33
MAPT P10636 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
FFAR4 Q5NUL3 1/20 0.32
HTT P42858 2/20 0.32
HCRTR1 O43613 2/20 0.32
HCRTR2 O43614 2/20 0.32
KMT2A Q03164 2/20 0.32
PTGS1 P23219 1/20 0.32
PTGS2 P35354 1/20 0.32
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10019360 0.97 POLB (0.34) SMN1; SMN2TDP1LMNAGAAPOLB
SCHEMBL19621901 0.91 CTSL (0.37) SMN1; SMN2TDP1LMNAGAAFFAR4
SCHEMBL10020051 0.91 CTSL (0.37) SMN1; SMN2TDP1LMNAGAAFFAR4
SCHEMBL10019368 0.89 CTSL (0.37) FFAR4
SCHEMBL15257974 0.88 KDM4E (0.39) LMNAALDH1A1KDM4EMAPTKMT2A
SCHEMBL10019878 0.87 KDM4E (0.41) SMN1; SMN2LMNAKDM4EMAPTFFAR4
SCHEMBL10020042 0.87 FFAR4 (0.31) FFAR4
SCHEMBL10019659 0.86 KDM4E (0.41) SMN1; SMN2LMNAKDM4EMAPTFFAR4
SCHEMBL15257973 0.85 MAPT (0.44) SMN1; SMN2ALDH1A1KDM4EMAPTFFAR4
SCHEMBL15257936 0.85 GABRA1 (0.35) SMN1; SMN2LMNAPOLBALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2669263-B1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2017-11-22 EP disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
WO-2012086437-A1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY JNC株式会社 (JP) 2012-06-28 WO disclosed